SCHEMBL565082

SCHEMBL565082

Nc1ccc(Cc2ccc(O)cc2)cc1O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.83
GAA P10253 2/20 0.83
MAPT P10636 2/20 0.83
MEN1 O00255 1/20 0.83
POLB P06746 1/20 0.83
RAB9A P51151 1/20 0.83
KMT2A Q03164 1/20 0.83
ESR1 P03372 3/20 0.58
ESR2 Q92731 3/20 0.58
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
IDH1 O75874 1/20 0.48
CYP3A4 P08684 3/20 0.47
ALOX15 P16050 3/20 0.46
HSD17B10 Q99714 2/20 0.46
ALDH1A1 P00352 5/20 0.46
CDC25B P30305 1/20 0.46
CASP6 P55212 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL436819 0.91 MAPT (1.00) KDM4EGAAMAPTMEN1POLB
SCHEMBL29871296 0.91 MAPT (1.00) KDM4EGAAMAPTMEN1POLB
SCHEMBL30350976 0.91 MAPT (1.00) KDM4EGAAMAPTMEN1POLB
Hydrochloric Acid SCHEMBL21173968 0.89 MAPT (0.95) KDM4EGAAMAPTMEN1POLB
SCHEMBL565037 0.88 MAPT (0.83) KDM4EGAAMAPTMEN1POLB
SCHEMBL564637 0.86 KDM4E (0.80) KDM4EGAAMAPTMEN1POLB
SCHEMBL8514724 0.83 GAA (0.83) KDM4EGAAMAPTMEN1POLB
SCHEMBL564633 0.83 ESR1 (0.58) KDM4EGAAMAPTMEN1POLB
SCHEMBL14889847 0.82 MEN1 (0.68) KDM4EGAAMAPTMEN1POLB
SCHEMBL564996 0.82 KDM4E (0.74) KDM4EGAAMAPTMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 KDM4E 3369/4885GAA 3993/4885MAPT 3886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.