SCHEMBL8514724

SCHEMBL8514724

Nc1cc(Cc2ccc(N)c(O)c2)ccc1O

nearest known ligand 0.83

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.83
MAPT P10636 3/20 0.83
KDM4E B2RXH2 2/20 0.83
MEN1 O00255 1/20 0.83
POLB P06746 1/20 0.83
RAB9A P51151 1/20 0.83
KMT2A Q03164 1/20 0.83
CA1 P00915 1/20 0.58
CA2 P00918 1/20 0.58
CA4 P22748 1/20 0.58
CA6 P23280 1/20 0.58
IDH1 O75874 1/20 0.48
ALDH1A1 P00352 6/20 0.47
GFER P55789 1/20 0.47
CYP3A4 P08684 2/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
ALOX15 P16050 4/20 0.46
HSD17B10 Q99714 4/20 0.46
CDC25B P30305 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564615 0.91 GAA (0.67) GAAMAPTKDM4EMEN1POLB
SCHEMBL436819 0.91 MAPT (1.00) GAAMAPTKDM4EMEN1POLB
SCHEMBL30350976 0.91 MAPT (1.00) GAAMAPTKDM4EMEN1POLB
SCHEMBL29860720 0.91 GAA (0.67) GAAMAPTKDM4EMEN1POLB
SCHEMBL29412587 0.91 GAA (0.67) GAAMAPTKDM4EMEN1POLB
SCHEMBL29871296 0.91 MAPT (1.00) GAAMAPTKDM4EMEN1POLB
Hydrochloric Acid SCHEMBL21173968 0.89 MAPT (0.95) GAAMAPTKDM4EMEN1POLB
Hydrochloric Acid SCHEMBL21173959 0.89 GAA (0.64) GAAMAPTKDM4EMEN1POLB
SCHEMBL565060 0.83 ALDH1A1 (0.58) GAAMAPTKDM4EMEN1POLB
SCHEMBL564633 0.83 ESR1 (0.58) GAAMAPTKDM4EMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160187776-A1 COMPOUND FOR SEMICONDUCTOR PACKAGE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME AND SEMICONDUCTOR PACKAGE STRUCTURE THEREOF GTA ELECTRONICS CO., LTD (TW) 2016-06-30 US disclosed
US-20120135251-A1 PHOTOSENSITIVE POLYIMIDE HAVING SILICON MODIFIED GROUP, ADHESIVE COMPOSITION AND SEMICONDUCTOR PACKAGE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160187776-A1 COMPOUND FOR SEMICONDUCTOR PACKAGE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME AND SEMICONDUCTOR PACKAGE STRUCTURE THEREOF SEM1, RER1, ASH2L GAA 2548/4885MAPT 1589/4885KDM4E 969/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.