SCHEMBL564996

SCHEMBL564996

Nc1ccc(Cc2cccc(O)c2)cc1O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.74
MAPT P10636 2/20 0.74
KMT2A Q03164 2/20 0.74
POLB P06746 2/20 0.74
MEN1 O00255 1/20 0.74
GAA P10253 1/20 0.74
RAB9A P51151 1/20 0.74
ENPP2 Q13822 1/20 0.52
IDH1 O75874 1/20 0.48
DRD2 P14416 1/20 0.48
DRD1 P21728 1/20 0.48
TAAR1 Q96RJ0 1/20 0.48
CYP3A4 P08684 4/20 0.47
ALOX15 P16050 2/20 0.47
CYP1A2 P05177 1/20 0.47
PKM P14618 1/20 0.47
NFKB1 P19838 1/20 0.47
MAPK1 P28482 1/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL564946 0.87 KDM4E (0.53) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL29871296 0.86 MAPT (1.00) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL436819 0.86 MAPT (1.00) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL30350976 0.86 MAPT (1.00) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL565515 0.85 KDM4E (0.74) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL564637 0.85 KDM4E (0.80) KDM4EMAPTKMT2APOLBMEN1
Hydrochloric Acid SCHEMBL21173968 0.84 MAPT (0.95) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL8514724 0.82 GAA (0.83) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL565082 0.82 KDM4E (0.83) KDM4EMAPTKMT2APOLBMEN1
SCHEMBL70267 0.82 ENPP2 (0.65) KDM4EMAPTKMT2AENPP2IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 KDM4E 3369/4885MAPT 3886/4885KMT2A 2278/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.