Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651575 | 0.89 | ALDH1A1 (0.57) | ALDH1A1POLBHTTLMNAP2RX7 | |
| SCHEMBL5651027 | 0.82 | ALDH1A1 (0.50) | ALDH1A1POLBHTTLMNAP2RX7 | |
| SCHEMBL5654716 | 0.82 | ALDH1A1 (0.54) | ALDH1A1POLBHTTP2RX7SLC6A2 | |
| SCHEMBL5654689 | 0.82 | ALDH1A1 (0.50) | ALDH1A1POLBHTTLMNAP2RX7 | |
| SCHEMBL5651024 | 0.79 | ALDH1A1 (0.47) | ALDH1A1POLBHTTLMNATHRB | |
| SCHEMBL12761225 | 0.71 | ALDH1A1 (0.62) | ALDH1A1POLBHTTLMNAP2RX7 | |
| SCHEMBL1154434 | 0.71 | ALDH1A1 (0.62) | ALDH1A1POLBHTTLMNAP2RX7 | |
| SCHEMBL5651126 | 0.71 | ALDH1A1 (0.62) | ALDH1A1POLBHTTLMNAP2RX7 | |
| SCHEMBL2491350 | 0.70 | CYP2D6 (1.00) | CYP2D6ALDH1A1HTTLMNATHRB | |
| SCHEMBL4403732 | 0.69 | P2RX7 (0.81) | ALDH1A1POLBHTTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070161691-A1 | Modified-protein formation inhibitor | TOKAI UNIVERSITY (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161691-A1 | Modified-protein formation inhibitor | TOKAI UNIVERSITY (JP) | 2007-07-12 | — | — | US | disclosed |
| US-20070161691-A1 | Modified-protein formation inhibitor | TOKAI UNIVERSITY (JP) | 2007-07-12 | — | — | US | disclosed |
| EP-1690857-A1 | MODIFIED-PROTEIN FORMATION INHIBITOR | TOKAI UNIVERSITY EDUCATIONAL SYSTEM (JP) | 2006-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161691-A1 | Modified-protein formation inhibitor | PTMS, ALB, AGER | CYP2D6 4178/4885ALDH1A1 3045/4885POLB 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.