Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | BMP1 | P13497 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5653634 | 0.85 | KMT2A (0.43) | KMT2AMEN1ALDH1A1ALKBH5FTO | |
| SCHEMBL13145848 | 0.85 | KEAP1 (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1ALKBH5 | |
| SCHEMBL3686840 | 0.77 | KMT2A (0.41) | SMN1; SMN2KMT2AMEN1ALDH1A1ALKBH5 | |
| SCHEMBL5651727 | 0.73 | LIPE (0.39) | KMT2AMEN1ALDH1A1THRB | |
| SCHEMBL5649603 | 0.72 | LIPE (0.38) | KMT2AMEN1ALDH1A1THRB | |
| SCHEMBL5650660 | 0.70 | ALKBH5 (0.43) | SMN1; SMN2KMT2AMEN1ALDH1A1ALKBH5 | |
| SCHEMBL20605302 | 0.68 | LIPE (0.40) | SMN1; SMN2KMT2AMEN1RAB9ATHRB | |
| SCHEMBL30627676 | 0.68 | MAPT (0.57) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL17140257 | 0.68 | KEAP1 (0.51) | ALDH1A1RAB9ABMP1MAPTMAPK1 | |
| SCHEMBL3565815 | 0.68 | SMN1; SMN2 (0.60) | SMN1; SMN2KMT2AMEN1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7223776-B2 | Compounds with anti-bacterial activity | MORPHOCHEM AG (DE) | 2007-05-29 | — | — | US | disclosed |
| US-20060040949-A1 | Novel compounds with antibacterial activity | MORPHOCHEM AG | 2006-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040949-A1 | Novel compounds with antibacterial activity | MRPL21, Q6ZSR9, MRPL19 | SMN1; SMN2 4680/4885KMT2A 4474/4885MEN1 4500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.