SCHEMBL565201

SCHEMBL565201

Nc1c(O)cccc1Oc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTNNB1 P35222 1/20 0.47
TTR P02766 2/20 0.44
DPP4 P27487 1/20 0.44
MAOB P27338 1/20 0.44
ADORA2A P29274 1/20 0.44
LTA4H P09960 2/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
MAOA P21397 1/20 0.43
HRH1 P35367 1/20 0.43
G6PD P11413 1/20 0.42
CASP7 P55210 1/20 0.42
CASP6 P55212 1/20 0.42
TSHR P16473 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42
NCOA1 Q15788 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31484717 0.92 G6PD (0.41) CTNNB1LTA4HNR1H2BAXMAOA
SCHEMBL563905 0.85 G6PD (0.45) G6PDCASP7CASP6TSHRALDH1A1
SCHEMBL6745256 0.83 LTA4H (0.50) CTNNB1DPP4MAOBADORA2ALTA4H
SCHEMBL396882 0.81 ALDH1A1 (0.52) CTNNB1TTRDPP4LTA4HNR1H2
SCHEMBL260447 0.81 TTR (0.57) CTNNB1TTRLTA4HNR1H2BAX
SCHEMBL29449754 0.81 TTR (0.57) CTNNB1TTRLTA4HNR1H2BAX
SCHEMBL6743039 0.80 TSHR (0.39) ADORA2AMAOAG6PDCASP7CASP6
Diphenylether SCHEMBL27888257 0.80 MAOB (0.48) MAOBLTA4HNR1H2BAXMAOA
SCHEMBL113777 0.79 GAA (0.52) CTNNB1DPP4MAOBADORA2ALTA4H
SCHEMBL31305020 0.79 GAA (0.52) CTNNB1DPP4MAOBADORA2ALTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
CN-101463128-B Polyarylether polymer containing amino-benzene lateral group and method for synthesizing the same JILIN UNIVERSITY (CN) 2011-12-07 CN disclosed
CN-101463128-A Polyarylether polymer containing amino-benzene lateral group and method for synthesizing the same UNIV JILIN (CN) 2009-06-24 CN disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 CTNNB1 3014/4885TTR 2796/4885DPP4 3596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.