SCHEMBL5652657

SCHEMBL5652657

O=C1OC(COC(=O)c2cc(Br)c(Br)s2)C=C1c1cccc(Br)c1

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.37
CSNK2B P67870 1/20 0.37
CSNK2A1 P68400 1/20 0.37
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
POLB P06746 1/20 0.35
PKM P14618 1/20 0.35
LMNA P02545 1/20 0.34
GSK3B P49841 2/20 0.33
CACNA1F O60840 1/20 0.31
ABCB1 P08183 1/20 0.31
CACNA1D Q01668 1/20 0.31
CACNA1S Q13698 1/20 0.31
CACNA1C Q13936 1/20 0.31
ALOX5 P09917 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5654011 0.90 CSNK2A2 (0.36) CSNK2A2CSNK2BCSNK2A1MEN1KMT2A
SCHEMBL5655483 0.86 CSNK2A2 (0.36) CSNK2A2CSNK2BCSNK2A1MEN1KMT2A
SCHEMBL5653106 0.84 POLB (0.42) MEN1KMT2AMAPTPOLBPKM
SCHEMBL5654798 0.84 MEN1 (0.36) CSNK2A2CSNK2BCSNK2A1MEN1KMT2A
SCHEMBL5653660 0.81 SMN1; SMN2 (0.42) MEN1KMT2AMAPTLMNA
SCHEMBL5666340 0.80 NLRP3 (0.39) MEN1KMT2AMAPTPOLBCACNA1F
SCHEMBL5654738 0.79 ELANE (0.36) MEN1KMT2ALMNACACNA1FABCB1
SCHEMBL5653859 0.78 L3MBTL1 (0.38) MEN1KMT2AMAPTLMNA
SCHEMBL5655563 0.78 CYP2D6 (0.40) MEN1KMT2AMAPTPOLBCACNA1F
SCHEMBL5655350 0.77 TGM2 (0.34) MEN1KMT2AMAPTPKMCACNA1F

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070259948-A1 Compounds with antifungal properties and process thereof FDC LIMITED (IN) 2007-11-08 US disclosed
US-20070259948-A1 Compounds with antifungal properties and process thereof FDC LIMITED (IN) 2007-11-08 US disclosed
US-20070259948-A1 Compounds with antifungal properties and process thereof FDC LIMITED (IN) 2007-11-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070259948-A1 Compounds with antifungal properties and process thereof ADH5, GK, AKR1C3 CSNK2A2 2506/4885CSNK2B 2393/4885CSNK2A1 1936/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.