SCHEMBL565289

SCHEMBL565289

Nc1cccc(Oc2ccccc2)c1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.49
ALDH1A1 P00352 2/20 0.49
CTNNB1 P35222 1/20 0.47
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
DPP4 P27487 1/20 0.44
MAOB P27338 1/20 0.44
LTA4H P09960 2/20 0.43
NR1H2 P55055 1/20 0.43
BAX Q07812 1/20 0.43
MAOA P21397 1/20 0.43
HRH1 P35367 1/20 0.43
RCE1 Q9Y256 1/20 0.43
BRD4 O60885 1/20 0.43
MMP2 P08253 1/20 0.42
TSHR P16473 1/20 0.42
HPGD P15428 1/20 0.42
NCOA1 Q15788 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL565066 0.85 MMP2 (0.45) GAAALDH1A1CYP1A2CYP3A4CYP2C9
SCHEMBL2916124 0.85 LTA4H (0.52) GAAALDH1A1CTNNB1DPP4LTA4H
SCHEMBL396882 0.81 ALDH1A1 (0.52) GAAALDH1A1CTNNB1CYP3A4DPP4
SCHEMBL5723 0.81 GAA (0.62) GAAALDH1A1CTNNB1CYP1A2CYP3A4
SCHEMBL30617018 0.81 GAA (0.62) GAAALDH1A1CTNNB1CYP1A2CYP3A4
SCHEMBL113777 0.79 GAA (0.52) GAAALDH1A1CTNNB1CYP1A2CYP3A4
SCHEMBL31305020 0.79 GAA (0.52) GAAALDH1A1CTNNB1CYP1A2CYP3A4
Hydrochloric Acid SCHEMBL50730 0.79 GAA (0.60) GAAALDH1A1CTNNB1CYP1A2CYP3A4
Diphenylether SCHEMBL9549269 0.79 GAA (0.60) GAAALDH1A1CTNNB1CYP1A2CYP3A4
SCHEMBL8852898 0.78 CYP1A2 (0.49) CTNNB1CYP1A2CYP3A4CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8674029-B2 Method of preparing stabilized polymeric systems using polymeric peroxides Sunocs LLC (US) 2014-03-18 US disclosed
US-20120035307-A1 PROCESS FOR MAKING STABLIZED POLYMERIC SYSTEMS WITH NANOSTRUCTURES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-20120035315-A1 METHOD OF PREPARING STABLIZED POLYMERIC SYSTEMS USING POLYMERIC PEROXIDES SONG CHENGQIAN (US) 2012-02-09 US disclosed
US-7498467-B2 Antioxidant and bisaminophenol derivative IDEMITSU KOSAN CO., LTD. (JP) 2009-03-03 US disclosed
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-07-03 US disclosed
US-20060208227-A1 Antioxidant and bisaminophenol derivative IDEMITSU LOSAN CO., LTD (JP) 2006-09-21 US disclosed
EP-1612254-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE IDEMITSU KOSAN COMPANY LIMITED (JP) 2006-01-04 EP disclosed
US-4208513-A Benzoxazolyl-phenylstilbenes, processes for producing them, and their use as optical brighteners CIBA-GEIGY CORPORATION (US) 1980-06-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161608-A1 ANTIOXIDANT AND BISAMINOPHENOL DERIVATIVE CBR1, CBR3, HMOX1 GAA 3993/4885ALDH1A1 204/4885CTNNB1 3014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.