⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11462369 | 0.82 | ALDH1A1 (0.48) | — | |
| SCHEMBL123985 | 0.74 | CA1 (0.48) | — | |
| SCHEMBL275849 | 0.74 | — | — | |
| SCHEMBL1031009 | 0.73 | — | — | |
| SCHEMBL164522 | 0.73 | — | — | |
| SCHEMBL2971139 | 0.73 | — | — | |
| SCHEMBL160523 | 0.73 | — | — | |
| SCHEMBL10530444 | 0.73 | — | — | |
| SCHEMBL1068357 | 0.73 | — | — | |
| SCHEMBL422932 | 0.72 | MAOA (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624126-A | Selective tyrosine kinase 2 (TYK 2) inhibitor compound, synthesis method and application | 中国药科大学 | 2024-03-01 | — | — | CN | disclosed |
| WO-2022100710-A1 | TYROSINE KINASE 2 (TYK2) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI) , INC. (CN) | 2022-05-19 | — | — | WO | disclosed |
| CN-105246884-A | Urea derivatives useful as kinase inhibitors | RESPIVERT LTD | 2016-01-13 | — | — | CN | disclosed |
| CN-104640861-A | Purinone compounds as kinase inhibitors | PHARMACYCLICS INC | 2015-05-20 | — | — | CN | disclosed |
| CN-101953755-B | Hair springiness and stiffness improving agent and hair cosmetic | SHISEIDO CO LTD | 2012-03-28 | — | — | CN | disclosed |
| WO-2011161201-A1 | BISARYLSULFONAMIDES USEFUL AS KINASE INHIBITORS IN THE TREATMENT OF INFLAMMATION AND CANCER | KANCERA AB (SE) | 2011-12-29 | — | — | WO | disclosed |
| CN-101953755-A | The tension force of hair and toughness improving agent and hair-dressing cosmetics | SHISEIDO CO LTD | 2011-01-26 | — | — | CN | disclosed |
| US-20070254917-A1 | INTRACELLULAR RECEPTOR MODULATOR COMPOUNDS AND METHODS | LIGAND PHARMACEUTICALS INC. | 2007-11-01 | — | — | US | disclosed |
| CN-101018552-A | Intracellular receptor modulator compounds and methods | LIGAND PHARM INC (US) | 2007-08-15 | — | — | CN | disclosed |
| EP-1355909-A2 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062795-A2 | DIHYDROPYRAZOLOPYRIDINE COMPOUNDS AND PHARMACEUTICAL USE THEREOF | MITSUBISHI PHARMA CORPORATION (JP) | 2002-08-15 | — | — | WO | disclosed |
| US-4338436-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4338439-A | BACTERICIDAL ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1982-07-06 | — | — | US | disclosed |
| US-4319028-A | 7-(2-(Substituted benzoyl)amino)acetamido)cephalosporins | ELI LILLY AND COMPANY (US) | 1982-03-09 | — | — | US | disclosed |