SCHEMBL5654520

SCHEMBL5654520

ClOc1cccc2cccnc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.58
RAB9A P51151 5/20 0.56
NPC1 O15118 4/20 0.56
MAPT P10636 3/20 0.54
LMNA P02545 6/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
CCR1 P32246 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4386263 0.83 KDM4E (0.72) KDM4ERAB9ANPC1MAPTLMNA
Hydrochloric Acid SCHEMBL27496748 0.81 KDM4E (0.59) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL28057988 0.80 RAB9A (0.61) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL3860121 0.79 KDM4E (0.58) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL22772422 0.79 KDM4E (0.58) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL170428 0.79 MEN1 (0.68) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL1878470 0.79 KDM4E (0.58) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL21753772 0.79 KDM4E (0.58) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL6516869 0.79 KDM4E (0.58) KDM4ERAB9ANPC1MAPTLMNA
SCHEMBL6750955 0.79 KDM4E (0.58) KDM4ERAB9ANPC1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4310930-A1 COMPOSITION, USE OF SAID COMPOSITION AS LIGHT-EMITTING COMPOSITION, FILM, USE OF SAID FILM AS LIGHT-EMITTING FILM, ORGANIC ELECTROLUMINESCNET ELEMENT, METHOD FOR DESIGNING COMPOSITION, AND PROGRAM FOR IMPLEMENTING SAID DESIGN METHOD Kyulux, Inc. (JP) 2024-01-24 EP disclosed
EP-3404735-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2023-05-10 EP disclosed
EP-4112655-A1 FLUORINE-CONTAINING POLYMER, FILM, FILM MANUFACTURING METHOD, AND ORGANIC OPTO-ELECTRONIC ELEMENT AGC INC. (JP) 2023-01-04 EP disclosed
WO-2021239191-A1 PERIMIDINE DERIVATIVES AND USE THEREOF TECHNISCHE UNIVERSITÄT BERGAKADEMIE FREIBERG (DE) 2021-12-02 WO disclosed
EP-3428152-B1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2021-11-03 EP disclosed
EP-3439062-B1 ORGANIC LIGHT EMITTING ELEMENT LG CHEMICAL LTD (KR) 2021-09-08 EP disclosed
WO-2021149773-A1 ORGANIC ELECTROLUMINESCENT ELEMENT 保土谷化学工業株式会社 2021-07-29 WO disclosed
WO-2021070965-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2021-04-15 WO disclosed
EP-3476833-B1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LG CHEMICAL LTD (KR) 2020-10-14 EP disclosed
WO-2019143151-A1 ORGANIC LIGHT-EMITTING DIODE 주식회사 엘지화학 2019-07-25 WO disclosed
WO-2019013437-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2019-01-17 WO disclosed
EP-3428163-A1 POLYCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed
EP-3428152-A1 COMPOUND AND ORGANIC ELECTRONIC ELEMENT COMPRISING SAME LG Chem, Ltd. (KR) 2019-01-16 EP disclosed
WO-2018139767-A1 NOVEL AMINE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2018-08-02 WO disclosed
EP-3339293-A1 COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG Chem, Ltd. (KR) 2018-06-27 EP disclosed
EP-3244464-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-11-15 EP disclosed
WO-2017115578-A1 ORGANIC ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME 大電株式会社 2017-07-06 WO disclosed
EP-3168887-A1 ORGANIC ELECTROLUMINESCENT ELEMENT Hodogaya Chemical Co., Ltd. (JP) 2017-05-17 EP disclosed
US-7220745-B2 Heterocyclic compounds useful to treat HCV RIGEL PHARMACEUTICALS (US) 2007-05-22 US disclosed
US-20040142985-A1 Heterocyclic compounds useful to treat HCV RIGEL PHARMACEUTICALS 2004-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040142985-A1 Heterocyclic compounds useful to treat HCV HAVCR2, PCNA, HCCS KDM4E 2617/4885RAB9A 3018/4885NPC1 368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.