SCHEMBL21753772

SCHEMBL21753772

[AlH2]Oc1cccc2cccnc12

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.58
RAB9A P51151 5/20 0.54
MAPT P10636 5/20 0.54
LMNA P02545 5/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
MMP2 P08253 2/20 0.54
TSHR P16473 2/20 0.54
CYP3A4 P08684 2/20 0.54
GMNN O75496 1/20 0.54
TP53 P04637 1/20 0.54
HSP90AA1 P07900 1/20 0.54
CYP2D6 P10635 1/20 0.54
MMP9 P14780 1/20 0.54
ALOX15 P16050 1/20 0.54
NFKB1 P19838 1/20 0.54
MMP8 P22894 1/20 0.54
CCR1 P32246 1/20 0.54
THPO P40225 1/20 0.54
MTOR P42345 1/20 0.54
HTT P42858 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27503445 1.00 KDM4E (0.58) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL4386263 0.83 KDM4E (0.72) KDM4ERAB9AMAPTLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL27496748 0.81 KDM4E (0.59) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL10051519 0.80 KDM4E (0.54) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL6750955 0.79 KDM4E (0.58) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL17924042 0.79 MAPT (0.59) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL22772422 0.79 KDM4E (0.58) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL6516869 0.79 KDM4E (0.58) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL3860121 0.79 KDM4E (0.58) KDM4ERAB9AMAPTLMNASMN1; SMN2
SCHEMBL1878470 0.79 KDM4E (0.58) KDM4ERAB9AMAPTLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114424358-B Organic electroluminescent element 索路思高新材料有限公司 2024-05-31 CN disclosed
CN-113166107-B Organic compound and organic electroluminescent element comprising same 索路思高新材料有限公司 2024-04-23 CN disclosed
CN-114728913-A Organic light-emitting compound and organic electroluminescent element using same 索路思高新材料有限公司 2022-07-08 CN disclosed
CN-114555566-A Organic compound and organic electroluminescent element comprising same 索路思高新材料有限公司 2022-05-27 CN disclosed
CN-114424358-A Organic electroluminescent element 索路思高新材料有限公司 2022-04-29 CN disclosed
CN-113195457-A Organic compound and organic electroluminescent element using same 索路思高新材料有限公司 2021-07-30 CN disclosed
CN-113166107-A Organic compound and organic electroluminescent element comprising same 索路思高新材料有限公司 2021-07-23 CN disclosed
US-20200321536-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2020-10-08 US disclosed
CN-111433927-A Compound for electron transport layer and organic electroluminescent element comprising same 斗山索如始株式会社 2020-07-17 CN disclosed
WO-2020039708-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT 国立大学法人九州大学 2020-02-27 WO disclosed
CN-101735107-A Aromatic amine compound, organic electroluminescent element including the same, and display device including organic electroluminescent element SONY CORP 2010-06-16 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200321536-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE L1CAM, LEF1, RPS12 KDM4E 2845/4885RAB9A 832/4885MAPT 1589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.