SCHEMBL565454

SCHEMBL565454

Cc1c(O)ccc(C(=O)O)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SELL P14151 1/20 0.64
SELP P16109 1/20 0.64
GRM1 Q13255 1/20 0.55
ALDH1A1 P00352 3/20 0.52
HSD17B10 Q99714 2/20 0.52
KDM4E B2RXH2 1/20 0.52
HPGD P15428 1/20 0.52
CSNK2A1 P68400 1/20 0.52
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
MAPT P10636 2/20 0.50
SHBG P04278 1/20 0.47
HTT P42858 2/20 0.46
ALOX15 P16050 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
MYC P01106 1/20 0.46
MCL1 Q07820 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
PDE4A P27815 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30463104 1.00 SELL (0.64) SELLSELPGRM1ALDH1A1HSD17B10
Ethylbenzene SCHEMBL10723361 0.84 MEN1 (0.50) SELLSELPGRM1ALDH1A1HSD17B10
SCHEMBL30443442 0.84 SELL (0.54) SELLSELPALDH1A1HSD17B10KDM4E
SCHEMBL317575 0.84 SELL (0.54) SELLSELPALDH1A1HSD17B10KDM4E
SCHEMBL1758260 0.84 KMT2A (0.51) SELLSELPALDH1A1HSD17B10KDM4E
SCHEMBL1669747 0.83 KMT2A (0.65) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL334851 0.82 MEN1 (0.50) SELLSELPALDH1A1HSD17B10KDM4E
SCHEMBL317576 0.82 ALDH1A1 (0.57) SELLSELPGRM1ALDH1A1HSD17B10
SCHEMBL30149140 0.82 ALDH1A1 (0.57) SELLSELPGRM1ALDH1A1HSD17B10
SCHEMBL29457560 0.82 MEN1 (0.50) SELLSELPALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1300488-B1 Plating path and method for depositing a metal layer on a substrate ROHM & HAAS ELECT MAT (US) 2017-09-27 EP claimed
US-8481519-B2 Isolation of atraric acid, synthesis of atraric acid derivatives, and use of atraric acid and the derivatives thereof for the treatment of benign prostatic hyperplasia, prostate carcinoma and spinobulbar muscular atrophy LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2013-07-09 US claimed
EP-1850857-B1 ISOLATION OF ATRARIC ACID, SYNTHESIS OF ATRARIC ACID DERIVATIVES, AND USE OF ATRARIC ACID AND THE DERIVATIVES THEREOF FOR THE TREATMENT OF PROSTATE CARCINOMA. LOHMANN THERAPIE SYST LTS (DE) 2013-05-22 EP claimed
US-20090143466-A1 Isolation of Atraric Acid, Synthesis of Atraric Acid Derivatives, and Use of Atraric Acid and the Derivatives Thereof for the Treatment of Benign Prostatic Hyperplasia, Prostate Carcinoma and Spinobulbar Muscular Atrophy LTS LOHMANN THERAPIE-SYSTEME AG (DE) 2009-06-04 US claimed
EP-1850857-A2 ISOLATION OF ATRARIC ACID, SYNTHESIS OF ATRARIC ACID DERIVATIVES, AND USE OF ATRARIC ACID AND THE DERIVATIVES THEREOF FOR THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA, PROSTATE CARCINOMA, AND SPINOBULBAR MUSCULAR ATROPHY LTS LOHMANN Therapie-Systeme AG (DE) 2007-11-07 EP claimed
WO-2006081997-A2 ISOLATION OF ATRARIC ACID, SYNTHESIS OF ATRARIC ACID DERIVATIVES, AND USE OF ATRARIC ACID AND THE DERIVATIVES THEREOF FOR THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA, PROSTATE CARCINOMA, AND SPINOBULBAR MUSCULAR ATROPHY LTS LOHMANN THERAPIE-SYSTEMS AG (DE) 2006-08-10 WO claimed
US-20050139118-A1 Brightener degradation inhibitor compound in copper plating bath SHIPLEY COMPANY, L.L.C. (US) 2005-06-30 US claimed
US-6911068-B2 Plating bath and method for depositing a metal layer on a substrate SHIPLEY COMPANY, L.L.C. (US) 2005-06-28 US claimed
US-20040206631-A1 Plating bath and method for depositing a metal layer on a substrate SHIPLEY COMPANY, L.L.C. 2004-10-21 US claimed
EP-1300488-A2 Plating path and method for depositing a metal layer on a substrate Shipley Co. L.L.C. (US) 2003-04-09 EP claimed
WO-2025202488-A1 ENHANCER OF NUCLEIC ACID AMPLIFICATION ROCHE DIAGNOSTICS GMBH (DE) 2025-10-02 WO disclosed
US-20250228811-A1 Triester Compounds And Methods Of Use Thereof LIFEMINE THERAPEUTICS, INC. 2025-07-17 US disclosed
WO-2025137071-A2 TRIESTER COMPOUNDS AND METHODS OF USE THEREOF LIFEMINE THERAPEUTICS, INC. (US) 2025-06-26 WO disclosed
US-20250188266-A1 MODIFIED PHENOLIC RESINS FOR MAKING COMPOSITE PRODUCTS Bakelite UK Holding Ltd. (GB) 2025-06-12 US disclosed
US-12303970-B2 Foundry mix including resorcinol Novis Works, LLC (US) 2025-05-20 US disclosed
US-5064914-A By transesterification; high melt strength; extrusion, blow molding GENERAL ELECTRIC COMPANY (US) 1991-11-12 US disclosed
EP-0384350-A1 Dihydroxy naphthalene derivatives F. HOFFMANN-LA ROCHE AG (CH) 1990-08-29 EP disclosed
EP-0351849-A2 Resist composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-01-24 EP disclosed
EP-0028063-B1 PHENOL DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM GLAXO GROUP LIMITED (GB) 1984-06-13 EP disclosed
EP-0028063-A1 Phenol derivatives, processes for their preparation and pharmaceutical compositions containing them GLAXO GROUP LIMITED (GB) 1981-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12303970-B2 Foundry mix including resorcinol PRRC2C, ASH2L, RCOR1 SELL 891/4885SELP 1923/4885GRM1 743/4885
US-20090143466-A1 Isolation of Atraric Acid, Synthesis of Atraric Acid Derivatives, and Use of Atraric Acid and the Derivatives Thereof for the Treatment of Benign Prostatic Hyperplasia, Prostate Carcinoma and Spinobulbar Muscular Atrophy RARB, RARA, AR SELL 4859/4885SELP 4771/4885GRM1 2105/4885
US-20250228811-A1 Triester Compounds And Methods Of Use Thereof CYP46A1, CYP17A1, CYP27A1 SELL 2288/4885SELP 1928/4885GRM1 3737/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.