SCHEMBL1669747

SCHEMBL1669747

Cc1c(O)ccc(C(=O)c2ccccc2C(=O)O)c1O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.65
CYP3A4 P08684 1/20 0.65
CYP2C9 P11712 1/20 0.65
ALDH1A1 P00352 6/20 0.58
AKR1C3 P42330 2/20 0.50
MEN1 O00255 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MAPT P10636 1/20 0.49
ALOX15 P16050 1/20 0.48
CDC25B P30305 3/20 0.47
HSD17B10 Q99714 2/20 0.47
CDC25A P30304 1/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HMGB1 P09429 1/20 0.47
CA4 P22748 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5303538 0.86 KMT2A (0.70) KMT2ACYP3A4CYP2C9ALDH1A1AKR1C3
SCHEMBL1758260 0.85 KMT2A (0.51) KMT2ACYP3A4CYP2C9ALDH1A1MEN1
SCHEMBL2865157 0.84 KMT2A (0.58) KMT2ACYP3A4CYP2C9ALDH1A1MEN1
SCHEMBL22939095 0.84 SELL (0.67) KMT2ACYP3A4CYP2C9ALDH1A1AKR1C3
SCHEMBL21812548 0.83 KMT2A (0.61) KMT2ACYP3A4CYP2C9ALDH1A1AKR1C3
SCHEMBL30463104 0.83 SELL (0.64) KMT2AALDH1A1MEN1MAPTALOX15
SCHEMBL565454 0.83 SELL (0.64) KMT2AALDH1A1MEN1MAPTALOX15
SCHEMBL22939098 0.82 KMT2A (0.59) KMT2ACYP3A4CYP2C9ALDH1A1AKR1C3
SCHEMBL2859239 0.82 MAPT (0.56) KMT2ACYP3A4ALDH1A1AKR1C3MEN1
SCHEMBL30331291 0.82 MAPT (0.56) KMT2ACYP3A4ALDH1A1AKR1C3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9506929-B2 Selective detection of amino group containing thiols PORTLAND STATE UNIVERSITY (US) 2016-11-29 US disclosed
US-9506929-B2 Selective detection of amino group containing thiols PORTLAND STATE UNIVERSITY (US) 2016-11-29 US disclosed
US-20150010938-A1 SELECTIVE DETECTION OF THIOLS OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2015-01-08 US disclosed
US-20150010938-A1 SELECTIVE DETECTION OF THIOLS OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2015-01-08 US disclosed
EP-2485900-B1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING INC (US) 2014-05-21 EP disclosed
WO-2013126816-A1 SELECTIVE DETECTION OF THIOLS OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OF PORTLAND STATE UNIVERSITY (US) 2013-08-29 WO disclosed
US-8372782-B2 Imaging system ZINK IMAGING, INC. (US) 2013-02-12 US disclosed
EP-2485900-A1 MULTICOLOUR THERMAL IMAGING MATERIAL Zink Imaging, Inc. (US) 2012-08-15 EP disclosed
EP-1597084-B1 IMAGING SYSTEM ZINK IMAGING LLC (US) 2012-04-11 EP disclosed
WO-2011044049-A1 MULTICOLOUR THERMAL IMAGING MATERIAL ZINK IMAGING, INC. (US) 2011-04-14 WO disclosed
CN-100448687-C Imaging unit and imaging method POLAROID CORP (US) 2009-01-07 CN disclosed
CN-101306613-A Color imaging method ZINK IMAGING LLC (US) 2008-11-19 CN disclosed
US-20070123421-A1 Imaging system ZINK IMAGING, LLC. 2007-05-31 US disclosed
US-7176161-B2 Containing crystalline compounds which produce color when thermally converted to liquid or amorphous form time-independent ZINK IMAGING, LLC (US) 2007-02-13 US disclosed
CN-1753793-A Imaging system POLAROID CORP (US) 2006-03-29 CN disclosed
EP-1597084-A2 IMAGING SYSTEM Polaroid Corporation (US) 2005-11-23 EP disclosed
US-20050186555-A1 Naphthofluorescein-based metal sensors, and methods of making and using the same NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-08-25 US disclosed
WO-2005067580-A2 NAPHTHOFLUORESCEIN-BASED METAL SENSORS, AND METHODS OF MAKING AND USING THE SAME MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-07-28 WO disclosed
WO-2004078479-A2 IMAGING SYSTEM POLAROID CORPORATION (US) 2004-09-16 WO disclosed
US-20040176248-A1 Imaging system ZINK HOLDINGS LLC 2004-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150010938-A1 SELECTIVE DETECTION OF THIOLS CBS, CTH, GSTM2 KMT2A 3686/4885CYP3A4 995/4885CYP2C9 88/4885
US-20050186555-A1 Naphthofluorescein-based metal sensors, and methods of making and using the same NCF1, NDUFV2, NQO1 KMT2A 3360/4885CYP3A4 1805/4885CYP2C9 3232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.