Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5652756 | 0.85 | F2 (0.36) | MAPK1TDP1APEX1F2PRSS1 | |
| SCHEMBL5655635 | 0.84 | TDP1 (0.38) | MAPK1TDP1APEX1F2PRSS1 | |
| SCHEMBL10717112 | 0.80 | ALDH1A1 (0.54) | MAPK1MAPTALDH1A1LMNA | |
| SCHEMBL5653955 | 0.79 | F2 (0.37) | F2PRSS1PRSS2PRSS3MAPT | |
| SCHEMBL1125078 | 0.78 | F2 (0.52) | MAPK1TDP1F2PRSS1PRSS2 | |
| SCHEMBL8470065 | 0.77 | MAPK1 (0.59) | MAPK1TDP1F2PRSS1PRSS2 | |
| SCHEMBL5655910 | 0.77 | MAPK1 (0.51) | MAPK1TDP1F2PRSS1PRSS2 | |
| SCHEMBL8854126 | 0.76 | PGR (0.45) | NFE2L2ALDH1A1PGR | |
| SCHEMBL5652655 | 0.75 | CA2 (0.44) | TDP1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5655158 | 0.74 | F2 (0.31) | MAPK1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030274-B2 | Process for the production of carbodiimide modified organic isocyanates | BAYER MATERIALSCIENCE LLC (US) | 2006-04-18 | — | — | US | disclosed |
| US-20050282993-A1 | Process for the production of carbodiimide modified organic isocyanates | COVESTRO LLC | 2005-12-22 | — | — | US | disclosed |
| EP-1607425-A1 | Process for the production of carboiimide modified organic isocyanates | Bayer MaterialScience LLC (US) | 2005-12-21 | — | — | EP | disclosed |
| US-6362247-B1 | DEACTIVATION PHOSPHOLENE CATALYSTS | ROHM AND HAAS COMPANY | 2002-03-26 | — | — | US | disclosed |
| EP-0721944-B1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LTD (JP) | 2001-01-17 | — | — | EP | disclosed |
| EP-1054029-A1 | Method of improving stability of aromatic polycarbodimides | ROHM AND HAAS COMPANY (US) | 2000-11-22 | — | — | EP | disclosed |
| CN-1273980-A | Method of improving stability of aromatic polycarbodi-imide | ROHM & HAAS (US) | 2000-11-22 | — | — | CN | disclosed |
| US-5691335-A | CARDIOVASCULAR DISORDERS | SUNTORY LIMITED (JP) | 1997-11-25 | — | — | US | disclosed |
| EP-0721944-A1 | IMIDAZOLIDINE DERIVATIVE AND USE THEREOF | SUNTORY LIMITED (JP) | 1996-07-17 | — | — | EP | disclosed |
| US-5045226-A | Reaction product of tin compound with sulfonyl isocyanate, storage stability, polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-03 | — | — | US | disclosed |
| EP-0172379-B1 | MATERIAL FOR ORTHOPAEDIC BANDAGES | BAYER AG (DE) | 1989-04-19 | — | — | EP | disclosed |
| US-4804655-A | Pesticidal cyclic malonylphosphonic diamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| EP-0132675-B1 | PREPARATIONS OF POLYISOCYNATE CONTAINING REVERSIBLY BLOCKED CATALYSTS, PROCESS FOR THEIR PRODUCTION, THEIR USE IN THE PRODUCTION OF POLYURETHANES, AND ADDITION PRODUCTS OF SULFONYLISOCYANATES ON CATALYSTS WITH A STRUCTURE OF CARBOXYLATES OF TIN II OR IV | BAYER AG (DE) | 1988-12-07 | — | — | EP | disclosed |
| EP-0240716-A2 | Bicyclic diazaphosphorus compounds, process for their preparation and their use as pesticides | BAYER AG (DE) | 1987-10-14 | — | — | EP | disclosed |
| EP-0231512-A1 | Cyclic malonylphosphonic acid diamides, process for their preparation and their use for pestcontrol | BAYER AG (DE) | 1987-08-12 | — | — | EP | disclosed |
| US-4638795-A | FOR MEDICAL AND VETERINARY USE; BASED ON POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| US-4614785-A | TERTIARY PHOSPHINE OR PERALKYLATED PHOSPHORUS ACID TRIAMIDE CATALYST | BAYER AKTIENGESELLSCHAFT (DE) | 1986-09-30 | — | — | US | disclosed |
| EP-0173252-A2 | Process for the preparation of oligomeric polyisocyanates and their use in the preparation of polyurethane plastics | BAYER AG (DE) | 1986-03-05 | — | — | EP | disclosed |
| EP-0172379-A1 | Material for orthopaedic bandages | BAYER AG (DE) | 1986-02-26 | — | — | EP | disclosed |
| EP-0132675-A2 | Preparations of polyisocynate containing reversibly blocked catalysts, process for their production, their use in the production of polyurethanes, and addition products of sulfonylisocyanates on catalysts with a structure of carboxylates of tin II or IV | BAYER AG (DE) | 1985-02-13 | — | — | EP | disclosed |