Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24316125 | 0.90 | MAPK1 (0.76) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL27563409 | 0.86 | LMNA (0.68) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL18409238 | 0.84 | FABP4 (0.77) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL11025784 | 0.82 | POLB (0.71) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL5655267 | 0.82 | POLB (0.71) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL13823016 | 0.81 | MAPK1 (0.64) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL428355 | 0.81 | MAPK1 (1.00) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL13593289 | 0.81 | POLB (0.60) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL13593351 | 0.81 | LMNA (0.74) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL10034910 | 0.81 | MAPK1 (0.68) | MAPK1POLBSMN1; SMN2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071214-B2 | Compounds and compositions for delivering active agents | EMISPHERE TECHNOLOGIES, INC. (US) | 2006-07-04 | — | — | US | disclosed |