SCHEMBL565547

SCHEMBL565547

CC(O)C(CCCN)C(C)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.40
TRPA1 O75762 1/20 0.40
SPHK1 Q9NYA1 1/20 0.34
GABRR1 P24046 2/20 0.33
TSHR P16473 2/20 0.33
CPB2 Q96IY4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GABBR2 O75899 1/20 0.32
GABBR1 Q9UBS5 1/20 0.32
ALDH1A1 P00352 1/20 0.32
NFKB1 P19838 1/20 0.32
GSR P00390 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4301189 0.92 TRPV1 (0.44) TRPV1TRPA1SPHK1TSHRCPB2
SCHEMBL24781 0.82
SCHEMBL565763 0.82 GABRR1 (0.42) TRPV1TRPA1SPHK1GABRR1TSHR
SCHEMBL6991138 0.82
SCHEMBL8397199 0.82
Ammonia Solution, Strong SCHEMBL27839768 0.80
Hydrochloric Acid SCHEMBL19066705 0.80
SCHEMBL3778830 0.78
SCHEMBL640973 0.77 NFKB1 (0.35) TRPV1TRPA1TSHRALDH1A1NFKB1
SCHEMBL16297104 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 296 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240207158-A1 DYEING COMPOSITION COMPRISING DIRECT DYES KAO CORPORATION (JP) 2024-06-27 US claimed
US-20240197606-A1 COSMETIC PRODUCT FOR DYEING KERATIN FIBERS KAO CORPORATION (JP) 2024-06-20 US claimed
EP-4221666-B1 HAIR DYEING COMPOSITION COMPRISING BLUE DYES KAO CORP (JP) 2024-06-12 EP claimed
EP-4329711-A1 DYEING COMPOSITION COMPRISING DIRECT DYES Kao Corporation (JP) 2024-03-06 EP claimed
US-20230270646-A1 HAIR DYEING COMPOSITION COMPRISING BLUE DYES KAO CORPORATION (JP) 2023-08-31 US claimed
EP-4221666-A1 HAIR DYEING COMPOSITION COMPRISING BLUE DYES Kao Corporation (JP) 2023-08-09 EP claimed
US-20230240421-A1 PROCESS FOR PERMANENT WAVING KERATIN FIBERS KAO GERMANY GMBH (DE) 2023-08-03 US claimed
EP-3710115-B1 PROCESS FOR PERMANENT WAVING KERATIN FIBERS KAO GERMANY GMBH (DE) 2023-06-14 EP claimed
EP-4178682-A1 PROCESS FOR PERMANENT WAVING KERATIN FIBERS Kao Germany GmbH (DE) 2023-05-17 EP claimed
WO-2023052512-A1 COMPOSITION COMPRISING AN OXIDATIVE DYE SALT KAO CORPORATION (JP) 2023-04-06 WO claimed
US-8840682-B2 Oxidizing composition for hair KAO GERMANY GMBH (DE) 2014-09-23 US claimed
EP-2658505-A2 OXIDIZING COMPOSITION FOR HAIR Kao Germany GmbH (DE) 2013-11-06 EP claimed
EP-2658506-A2 OXIDIZING COMPOSITION FOR HAIR Kao Germany GmbH (DE) 2013-11-06 EP claimed
US-20130269722-A1 OXIDIZING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2013-10-17 US claimed
US-20130263878-A1 OXIDIZING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2013-10-10 US claimed
WO-2013098207-A1 OXIDATIVE DYEING COMPOSITION KAO GERMANY GMBH (DE) 2013-07-04 WO claimed
WO-2012089664-A2 OXIDIZING COMPOSITION FOR HAIR KAO GERMANY GMBH (DE) 2012-07-05 WO claimed
WO-2012089665-A2 OXIDIZING COMPOSITION FOR HAIR KPSS-KAO PROFESSIONAL SALON SERVICES GMBH (DE) 2012-07-05 WO claimed
EP-2468240-A1 Oxidizing composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2012-06-27 EP claimed
EP-2417959-A1 Oxidizing composition for hair KPSS-Kao Professional Salon Services GmbH (DE) 2012-02-15 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197606-A1 COSMETIC PRODUCT FOR DYEING KERATIN FIBERS KRT18, H1-4, H1-0 TRPV1 558/4885TRPA1 259/4885SPHK1 4074/4885
US-20230270646-A1 HAIR DYEING COMPOSITION COMPRISING BLUE DYES KRT18, TUBB8, TYR TRPV1 1753/4885TRPA1 1258/4885SPHK1 4352/4885
US-20130263878-A1 OXIDIZING COMPOSITION FOR HAIR KRT18, OAT, COXFA4L2 TRPV1 1251/4885TRPA1 1495/4885SPHK1 3725/4885
US-20130269722-A1 OXIDIZING COMPOSITION FOR HAIR KRT18, OAT, COXFA4L2 TRPV1 1251/4885TRPA1 1495/4885SPHK1 3725/4885
US-20240207158-A1 DYEING COMPOSITION COMPRISING DIRECT DYES KRT18, IK, H1-3 TRPV1 1526/4885TRPA1 1437/4885SPHK1 4104/4885
US-20230240421-A1 PROCESS FOR PERMANENT WAVING KERATIN FIBERS KRT18, WNK2, WNK1 TRPV1 1524/4885TRPA1 2191/4885SPHK1 3132/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.