Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5655728 | 0.94 | TSHR (0.55) | TSHRLMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL5658365 | 0.87 | HTR1A (0.56) | MAPTTP53DRD3DRD2HTR2A | |
| SCHEMBL5655859 | 0.87 | GFER (0.55) | MAPTPOLBTP53DRD3HTR2A | |
| SCHEMBL5655713 | 0.86 | MEN1 (0.57) | TSHRLMNAMAPTALOX15USP2 | |
| SCHEMBL5656003 | 0.86 | KCNH2 (0.52) | MAPTHTTPOLBTP53HSD17B10 | |
| SCHEMBL5657582 | 0.85 | LMNA (0.55) | LMNAMAPTKDM4ETP53HSD17B10 | |
| SCHEMBL5656794 | 0.83 | HTR1A (0.54) | MAPTPOLBDRD2 | |
| SCHEMBL5658289 | 0.82 | HTR1A (0.58) | MAPTTP53DRD3DRD2HTR2A | |
| SCHEMBL5657422 | 0.81 | HTR1A (0.57) | MAPTHTTKDM4EPOLBSIGMAR1 | |
| SCHEMBL5655788 | 0.81 | POLB (0.51) | TSHRLMNAMAPTPOLBDRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |