Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.52 |
| ▸ | DRD4 | P21917 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5658365 | 0.94 | HTR1A (0.56) | HTR1AKCNH2TP53MAPTDRD3 | |
| SCHEMBL5657645 | 0.92 | HTR1A (0.57) | HTR1AKCNH2TP53MAPTDRD3 | |
| SCHEMBL5657861 | 0.92 | OPRM1 (0.55) | HTR1AKCNH2HTR2ADRD2 | |
| SCHEMBL5657423 | 0.91 | KCNH2 (0.56) | HTR1AKCNH2DRD3HTR2ADRD2 | |
| SCHEMBL5658364 | 0.90 | HTR2A (0.58) | HTR1ADRD3HTR2ADRD2DRD4 | |
| SCHEMBL5655728 | 0.88 | TSHR (0.55) | TP53MAPTDRD3HTR2ADRD2 | |
| SCHEMBL5656201 | 0.86 | HTR1A (0.55) | HTR1AKCNH2TP53MAPTDRD3 | |
| SCHEMBL5657065 | 0.86 | ALDH1A1 (0.51) | HTR1AMAPTDRD3HTR2ADRD2 | |
| SCHEMBL5656281 | 0.86 | OPRM1 (0.52) | HTR1ADRD2DRD4 | |
| SCHEMBL5657619 | 0.86 | HTR7 (0.51) | MAPTDRD3HTR2ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20040058933-A1 | Aryl carbamate derivatives, preperation and use thereof | CEREP (FR) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058933-A1 | Aryl carbamate derivatives, preperation and use thereof | HTR4, HTR5A, HTR3C | HTR1A 8/4885KCNH2 1144/4885TP53 4247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.