Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657065 | 0.94 | ALDH1A1 (0.51) | HTR1ACYP3A4CYP2D6ADRA1AALDH1A1 | |
| SCHEMBL5655859 | 0.93 | GFER (0.55) | HTR1ACYP3A4CYP2D6ADRA1AMEN1 | |
| SCHEMBL5657422 | 0.91 | HTR1A (0.57) | HTR1AALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL5655788 | 0.91 | POLB (0.51) | HTR1ACYP3A4CYP2D6ADRA1AALDH1A1 | |
| SCHEMBL5657925 | 0.90 | MAPT (0.54) | HTR1AMAPTPOLBGFERDRD4 | |
| SCHEMBL5657553 | 0.89 | HTR1A (0.48) | HTR1ACYP3A4CYP2D6ADRA1AALDH1A1 | |
| SCHEMBL5657861 | 0.87 | OPRM1 (0.55) | HTR1AALDH1A1POLBGFERDRD2 | |
| SCHEMBL5654959 | 0.86 | HTR1A (0.55) | HTR1ACYP3A4CYP2D6ADRA1AALDH1A1 | |
| SCHEMBL5656387 | 0.85 | HTR1A (0.61) | HTR1ACYP3A4CYP2D6ADRA1AALDH1A1 | |
| SCHEMBL5658365 | 0.85 | HTR1A (0.56) | HTR1AMEN1KMT2AMAPTGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |
| US-20040058933-A1 | Aryl carbamate derivatives, preperation and use thereof | CEREP (FR) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058933-A1 | Aryl carbamate derivatives, preperation and use thereof | HTR4, HTR5A, HTR3C | HTR1A 8/4885CYP3A4 60/4885CYP2D6 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.