Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3757586 | 0.86 | NPC1 (0.52) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL3769883 | 0.82 | MEN1 (0.56) | KMT2AMEN1NPC1RAB9A | |
| SCHEMBL1697310 | 0.76 | NPC1 (0.43) | KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL6773752 | 0.76 | RAB9A (0.46) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL5655622 | 0.75 | NPC1 (0.44) | NPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL5186000 | 0.75 | NPC1 (0.47) | APOBEC3AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL1003665 | 0.74 | KMT2A (0.83) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL29797867 | 0.73 | NPC1 (0.56) | NPC1RAB9A | |
| SCHEMBL180384 | 0.73 | NPC1 (0.73) | KMT2AMEN1NPC1RAB9ACA12 | |
| SCHEMBL12852370 | 0.73 | MEN1 (0.54) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7229991-B2 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxamides | GRUENENTHAL GMBH (DE) | 2007-06-12 | — | — | US | disclosed |
| US-20050288342-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxamides | GRUENENTHAL GMBH (DE) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288342-A1 | Substituted 5-aminomethyl-1H-pyrrole-2-carboxamides | QPCT, PGA5, ALDH18A1 | APOBEC3A 3261/4885KMT2A 1319/4885MEN1 2422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.