Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 2/20 | 0.39 |
| ▸ | CTSV | O60911 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182509 | 0.80 | L3MBTL1 (0.49) | DHODHTHRATHRBBRD4TDP1 | |
| SCHEMBL30789279 | 0.76 | PKM (0.58) | CYP19A1CTSVCTSLL3MBTL1MEN1 | |
| SCHEMBL25368475 | 0.74 | THRA (0.43) | CYP19A1PPIACTSVCTSLTHRA | |
| SCHEMBL8902020 | 0.73 | AR (0.39) | THRBTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL16738929 | 0.72 | AR (0.38) | THRBTDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL5659575 | 0.72 | CYP19A1 (0.42) | CYP19A1DHODHTHRATHRBMGMT | |
| SCHEMBL30510897 | 0.72 | CYP19A1 (0.43) | CYP19A1PPIACTSVCTSLTHRA | |
| SCHEMBL26039527 | 0.72 | CYP19A1 (0.43) | CYP19A1PPIACTSVCTSLTHRA | |
| SCHEMBL26618577 | 0.71 | KMT2A (0.45) | THRBL3MBTL1MEN1KMT2AMAPT | |
| SCHEMBL25367087 | 0.71 | MGMT (0.44) | CYP19A1PPIACTSVCTSLTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307084-B2 | Cyclic benzimidazoles | ALTANA PHARMA AG (DE) | 2007-12-11 | — | — | US | disclosed |
| US-20060194968-A1 | Cyclic benizimidazoles | ALTANA PHARMA AG (DE) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194968-A1 | Cyclic benizimidazoles | VIP, SI, GIPR | CYP19A1 540/4885PPIA 1514/4885DHODH 2936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.