SCHEMBL56565

SCHEMBL56565

O=C(OCc1ccccc1)c1cccc(O)c1

nearest known ligand 0.82

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.82
NPC1 O15118 3/20 0.82
TDP1 Q9NUW8 4/20 0.73
KMT2A Q03164 3/20 0.73
SLC6A2 P23975 1/20 0.73
SLC6A3 Q01959 1/20 0.73
LMNA P02545 4/20 0.67
ALDH1A1 P00352 5/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
KDM4E B2RXH2 1/20 0.59
MAPT P10636 2/20 0.57
HTT P42858 1/20 0.54
HPGD P15428 1/20 0.54
ESR1 P03372 1/20 0.54
ESR2 Q92731 1/20 0.54
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA6 P23280 1/20 0.53
CA9 Q16790 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL312910 0.91 TDP1 (0.81) RAB9ANPC1TDP1KMT2ASLC6A2
SCHEMBL24515889 0.89 RAB9A (0.67) RAB9ANPC1TDP1KMT2ASLC6A2
SCHEMBL181934 0.86 TDP1 (0.73) RAB9ANPC1TDP1KMT2ASLC6A2
SCHEMBL9696689 0.86 TDP1 (0.72) RAB9ANPC1TDP1KMT2ASLC6A2
SCHEMBL9166162 0.86 TDP1 (0.72) RAB9ANPC1TDP1KMT2ASLC6A2
SCHEMBL10980613 0.85 ESR1 (0.69) RAB9ANPC1TDP1KMT2ASLC6A2
Benzyl Benzoate SCHEMBL3038 0.85 KMT2A (1.00) RAB9ANPC1TDP1KMT2ASLC6A2
Benzyl Benzoate SCHEMBL901058 0.85 KMT2A (1.00) RAB9ANPC1TDP1KMT2ASLC6A2
Benzyl Benzoate SCHEMBL8010992 0.85 KMT2A (1.00) RAB9ANPC1TDP1KMT2ASLC6A2
SCHEMBL318600 0.85 TDP1 (0.71) RAB9ANPC1TDP1KMT2ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114989501-A Non-toxic environment-friendly foamed natural rubber and preparation method thereof 唐雪金 2022-09-02 CN claimed
CN-108635361-B A flos Viburni Sargentii extract with antiinflammatory activity, and its active ingredient and separation method 扬州大学 2020-02-07 CN claimed
JP-5078610-A None JP disclosed
JP-59042998-A None JP disclosed
CN-117794526-A Compositions and methods for antioxidants and anti-inflammatory therapeutics 阿万蒂生物科学股份有限公司 2024-03-29 CN disclosed
CN-108472381-B Compounds and therapeutic uses thereof 森陶里治疗有限公司 2023-06-06 CN disclosed
CN-114989501-A Non-toxic environment-friendly foamed natural rubber and preparation method thereof 唐雪金 2022-09-02 CN disclosed
CN-109456324-B Isoindoline or isoquinoline compounds, process for their preparation and pharmaceutical compositions containing them 法国施维雅药厂 2022-04-22 CN disclosed
US-20210369850-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF Centauri Therapeutics Limited (GB/GB) (GB) 2021-12-02 US disclosed
US-11028070-B2 Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them LES LABORATOIRES SERVIER (FR) 2021-06-08 US disclosed
US-10953100-B2 Compounds and therapeutic uses thereof CENTUARI THERAPEUTICS LIMITED (GB/GB) (GB) 2021-03-23 US disclosed
EP-0749316-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1996-12-27 EP disclosed
WO-1995023608-A1 ANTITHROMBOTIC AGENTS ELI LILLY AND COMPANY (US) 1995-09-08 WO disclosed
JP-H0578610-A INK COMPOSITION FOR INK JET RECORDING RICOH CO LTD 1993-03-30 JP disclosed
EP-0249885-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1992-01-02 EP disclosed
US-4794101-A MIXTURE OF PHTHALIDE DYE, FLUORAN COMPOUND AND POLYVALENT METAL SALT OF AN AROMATIC CARBOXYLIC ACID KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-12-27 US disclosed
EP-0249885-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-12-23 EP disclosed
JP-S5942998-A HEAT SENSITIVE RECORDING MATERIAL RICOH CO LTD 1984-03-09 JP disclosed
US-4348410-A Cyclohexane carboxylic acid derivatives NIPPON CHEMIPHAR CO., LTD. (JP) 1982-09-07 US disclosed
US-4145342-A NITRO-DIPHENYLAMINO-AZO-PHENYL DYESTUFFS CONTAINING A POLYALKYENEOXY GROUP BAYER AKTIENGESELLSCHAFT (DE) 1979-03-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369850-A1 COMPOUNDS AND THERAPEUTIC USES THEREOF CD47, MYD88, NFATC1 RAB9A 1262/4885NPC1 583/4885TDP1 2823/4885
US-10953100-B2 Compounds and therapeutic uses thereof CD47, MYD88, NFATC1 RAB9A 1262/4885NPC1 583/4885TDP1 2823/4885
US-11028070-B2 Isoindoline or isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them BAX, RECQL, CASP7 RAB9A 139/4885NPC1 1358/4885TDP1 1009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.