Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657861 | 0.86 | OPRM1 (0.55) | HTR7ALDH1A1SIGMAR1OPRM1KDM4E | |
| SCHEMBL5655837 | 0.85 | DRD2 (0.63) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL5654725 | 0.85 | DRD2 (0.55) | ALDH1A1KDM4ETDP1MEN1KMT2A | |
| SCHEMBL5655983 | 0.84 | MAPT (0.53) | HTR7SIGMAR1OPRM1 | |
| SCHEMBL5659495 | 0.84 | OPRM1 (0.50) | ALDH1A1OPRM1KDM4ETDP1MEN1 | |
| SCHEMBL5655926 | 0.83 | DRD2 (0.55) | HTR7ALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL5658364 | 0.83 | HTR2A (0.58) | HTR7ALDH1A1SIGMAR1OPRM1KDM4E | |
| SCHEMBL5657065 | 0.83 | ALDH1A1 (0.51) | HTR7ALDH1A1SIGMAR1OPRM1 | |
| SCHEMBL5656281 | 0.83 | OPRM1 (0.52) | OPRM1 | |
| SCHEMBL5657619 | 0.83 | HTR7 (0.51) | HTR7OPRM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238693-B2 | Aryl carbamate derivatives, preparation and use thereof | CEREP (FR) | 2007-07-03 | — | — | US | disclosed |