Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.48 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1287678 | 0.85 | EPHX1 (0.55) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL523308 | 0.78 | EPHX1 (0.48) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL8780026 | 0.76 | TRPA1 (0.54) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL8660787 | 0.76 | EPHX1 (0.46) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL1376582 | 0.76 | TRPA1 (0.50) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL516032 | 0.75 | EPHX1 (0.56) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL6563096 | 0.75 | EPHX1 (0.56) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL351709 | 0.75 | EPHX1 (0.64) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL1007428 | 0.75 | EPHX1 (0.50) | EPHX1TAAR1SLC6A2CYP2A6MAOA | |
| SCHEMBL6931237 | 0.75 | EPHX1 (0.64) | EPHX1TAAR1SLC6A2CYP2A6MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1863530-A | (3,4-phenyl)piperidin-3-yl- phenylcarboxylate derivatives and related compounds as beta-secretase inhibitors for the treatment of alzheimer's disease | ELAN PHARM INC (US) | 2006-11-15 | — | — | CN | claimed |
| CN-104145212-A | Composition for forming liquid crystal alighment film and liquid crystal display element | SOKI CORP | 2014-11-12 | — | — | CN | disclosed |
| CN-101914040-A | Acyloxyalkyl carbamate prodrugs, synthetic method and purposes | XENOPORT INC | 2010-12-15 | — | — | CN | disclosed |
| CN-1860101-B | Acyloxyalkyl carbamate prodrugs, synthesis methods and uses | XENOPORT INC | 2010-10-27 | — | — | CN | disclosed |
| CN-101001612-A | Controlled release dosage forms for gamma aminobutyric acid receptor agonists | IMPAX LABORATORIES INC (US) | 2007-07-18 | — | — | CN | disclosed |
| CN-1863530-A | (3,4-phenyl)piperidin-3-yl- phenylcarboxylate derivatives and related compounds as beta-secretase inhibitors for the treatment of alzheimer's disease | ELAN PHARM INC (US) | 2006-11-15 | — | — | CN | disclosed |
| CN-1860101-A | Acyloxyalkyl carbamate prodrugs, synthesis methods and uses | XENOPORT INC (US) | 2006-11-08 | — | — | CN | disclosed |
| EP-1401423-A4 | METHOD OF TREATING GASTROESOPHAGEAL REFLUX DISEASE AND NOCTURNAL ACID BREAKTHROUGH | DEPOMED DEV LTD (BM) | 2006-08-16 | — | — | EP | disclosed |
| EP-1401423-A1 | METHOD OF TREATING GASTROESOPHAGEAL REFLUX DISEASE AND NOCTURNAL ACID BREAKTHROUGH | Depomed Development, Ltd (GB) | 2004-03-31 | — | — | EP | disclosed |
| CN-1117560-C | Reflux inhibitors | ASTRA AB (SE) | 2003-08-13 | — | — | CN | disclosed |
| US-20030031711-A1 | Method of treating gastroesophageal reflux disease and nocturnal acid breakthrough | ASSERTIO THERAPEUTICS, INC. | 2003-02-13 | — | — | US | disclosed |
| WO-2002096404-A1 | METHOD OF TREATING GASTROESOPHAGEAL REFLUX DISEASE AND NOCTURNAL ACID BREAKTHROUGH | DEPOMED DEVELOPMENT LTD (GB) | 2002-12-05 | — | — | WO | disclosed |
| CN-1237105-A | Reflux inhibitors | ASTRA AB (SE) | 1999-12-01 | — | — | CN | disclosed |