Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 16/20 | 0.62 |
| ▸ | CXCR1 | P25024 | 14/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657717 | 0.92 | CXCR2 (0.58) | CXCR2CXCR1MEN1LMNAKMT2A | |
| SCHEMBL5660485 | 0.89 | CXCR2 (0.77) | CXCR2CXCR1MEN1LMNAKMT2A | |
| SCHEMBL5845430 | 0.88 | CXCR2 (0.81) | CXCR2CXCR1 | |
| SCHEMBL5656795 | 0.82 | CXCR2 (0.76) | CXCR2CXCR1MEN1LMNAKMT2A | |
| SCHEMBL5656391 | 0.82 | CXCR1 (0.75) | CXCR2CXCR1MEN1KMT2A | |
| SCHEMBL5660344 | 0.82 | CXCR1 (0.57) | CXCR2CXCR1 | |
| SCHEMBL5658349 | 0.81 | CXCR2 (0.73) | CXCR2CXCR1NPC1RAB9A | |
| SCHEMBL5656328 | 0.80 | P4HTM (0.57) | CXCR2CXCR1NPC1RAB9A | |
| SCHEMBL5659934 | 0.80 | CXCR2 (0.61) | CXCR2CXCR1 | |
| SCHEMBL5661579 | 0.79 | CXCR2 (0.57) | CXCR2CXCR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176310-B1 | Pyrimidinecarboxamide derivatives and their use as anti-inflammatory agents | UCB SA (GB) | 2007-02-13 | — | — | US | disclosed |