Hydrochloric Acid

Hydrochloric Acid

SCHEMBL566069

C=C(C)C(=O)NCCC[N+](C)(C)C.C=CO.[Cl-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 1/20 0.37
CHRM1 known ✓ P11229 2/20 0.35
CHRM3 known ✓ P20309 2/20 0.35
CHRM2 known ✓ P08172 1/20 0.32
ATM Q13315 2/20 0.36
KMT2A Q03164 1/20 0.36
CHRM5 P08912 2/20 0.35
APOBEC3A P31941 1/20 0.33
APOBEC3G Q9HC16 1/20 0.33
PGR P06401 1/20 0.32
CHRM4 P08173 1/20 0.32
HTR1A P08908 1/20 0.32
CHRNB2 P17787 1/20 0.32
TBXA2R P21731 1/20 0.32
CHRNB4 P30926 1/20 0.32
CHRNA3 P32297 1/20 0.32
CHRNA7 P36544 1/20 0.32
CHRNA4 P43681 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CHRNA10 Q9GZZ6 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27571208 0.93 ACHE (0.42) ACHEATMKMT2ACHRM5CHRM1
Hydrochloric Acid SCHEMBL61004 0.93 ACHE (0.42) ACHEATMKMT2ACHRM5CHRM1
Hydrochloric Acid SCHEMBL1201070 0.91 ACHE (0.41) ACHEATMKMT2ACHRM5CHRM1
SCHEMBL25422694 0.91 ACHE (0.43) ACHEATMKMT2ACHRM5CHRM1
SCHEMBL33607 0.91 ACHE (0.43) ACHEATMKMT2ACHRM5CHRM1
Hydrochloric Acid SCHEMBL28176347 0.90 ACHE (0.39) ACHEATMKMT2ACHRM5CHRM1
Fluoride Ion SCHEMBL8578974 0.90 ACHE (0.42) ACHEATMKMT2ACHRM5CHRM1
Hydrochloric Acid SCHEMBL21827668 0.90 ACHE (0.42) ACHEATMKMT2ACHRM5CHRM1
Bromide SCHEMBL718176 0.90 ACHE (0.42) ACHEATMKMT2ACHRM5CHRM1
Iodide SCHEMBL23607568 0.90 ACHE (0.42) ACHEATMKMT2ACHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9346020-B2 Multilayered charge-mosaic membrane and manufacturing method therefor KURARAY CO., LTD. (JP) 2016-05-24 US disclosed
US-9266069-B2 Ion-exchange membrane and method for producing same YAMAGUCHI UNIVERSITY (JP) 2016-02-23 US disclosed
US-20150239756-A1 ELECTRODE, METHOD FOR PRODUCING SAME, AND FLOW-THROUGH CAPACITOR INCLUDING SAME KURARAY CO., LTD. (JP) 2015-08-27 US disclosed
EP-2896600-A1 ELECTRODE, METHOD FOR PRODUCING SAME, AND FLOW-THROUGH CAPACITOR INCLUDING SAME Kuraray Co., Ltd. (JP) 2015-07-22 EP disclosed
US-20120285881-A1 MULTILAYERED CHARGE-MOSAIC MEMBRANE AND MANUFACTURING METHOD THEREFOR YAMAGUCHI UNIVERSITY (JP) 2012-11-15 US disclosed
EP-2520357-A1 MULTILAYERED CHARGE-MOSAIC MEMBRANE AND MANUFACTURING METHOD THEREFOR Kuraray Co., Ltd. (JP) 2012-11-07 EP disclosed
EP-2420310-A1 ION-EXCHANGE MEMBRANE AND METHOD FOR PRODUCING SAME Yamaguchi University (JP) 2012-02-22 EP disclosed
US-20120031834-A1 ION-EXCHANGE MEMBRANE AND METHOD FOR PRODUCING SAME KURARAY CO., LTD. (JP) 2012-02-09 US disclosed