Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 2/20 | 0.44 |
| ▸ | GABRD | O14764 | 2/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | GABRE | P78334 | 2/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29378242 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 | |
| Hydrochloric Acid SCHEMBL2523036 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 | |
| Water SCHEMBL28081708 | 0.98 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 | |
| Nitrous Acid SCHEMBL27924301 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 | |
| Dimethylamine SCHEMBL31596354 | 0.92 | SMN1; SMN2 (0.44) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 | |
| SCHEMBL15530203 | 0.83 | GABRP (0.60) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 | |
| SCHEMBL29375536 | 0.82 | SLC6A12 (0.38) | SMN1; SMN2LMNAKEAP1NFE2L2NAPRT | |
| SCHEMBL671978 | 0.82 | SLC6A12 (0.38) | SMN1; SMN2LMNAKEAP1NFE2L2NAPRT | |
| SCHEMBL20532004 | 0.81 | SLC6A12 (0.36) | SMN1; SMN2LMNAKEAP1NFE2L2GABRP | |
| SCHEMBL7897938 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2LMNAKEAP1NFE2L2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2339 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119857302-B | Filtering device for cleaning impurities in preparation process of dichloronicotinic acid | 甘肃安隆科技有限公司 | 2025-05-23 | — | — | CN | claimed |
| CN-119857302-A | Filtering device for cleaning impurities in preparation process of dichloronicotinic acid | 甘肃安隆科技有限公司 | 2025-04-22 | — | — | CN | claimed |
| US-12202813-B2 | Process for preparing 6-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)nicotinamide | BEIJING INNOCARE PHARMA TECH CO., LTD (CN) | 2025-01-21 | — | — | US | claimed |
| CN-118912845-A | Drying equipment is used in dichloro nicotinic acid production | 宁夏永利新材料有限公司 | 2024-11-08 | — | — | CN | claimed |
| CN-221693002-U | Device for recycling and treating waste liquid of dichloro nicotinic acid | 沈瑞雪 | 2024-09-13 | — | — | CN | claimed |
| CN-108404459-B | Sewage pretreatment device for dichloronicotinic acid production | 浙江荣凯科技发展股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-220918709-U | Chlorine processing apparatus is used in dichloro nicotinic acid production | 重庆增程科技有限公司 | 2024-05-10 | — | — | CN | claimed |
| CN-220750613-U | Novel suction filtration drying device for dichloronicotinic acid | 重庆增程科技有限公司 | 2024-04-09 | — | — | CN | claimed |
| CN-113454066-B | Process for preparing 6- (1-propenoylpiperidin-4-yl) -2- (4-phenoxyphenyl) nicotinamide | 北京诺诚健华医药科技有限公司 | 2024-02-09 | — | — | CN | claimed |
| CN-220345660-U | Dichloro nicotinic acid mixing arrangement convenient to fragment | 重庆增程科技有限公司 | 2024-01-16 | — | — | CN | claimed |
| CN-205420240-U | Mechanical device of production dichloro nicotinic acid | 徐州永利精细化工有限公司 | 2016-08-03 | — | — | CN | claimed |
| US-8497282-B2 | Method of preparing (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | SUNESIS PHARMACEUTICALS, INC. (US) | 2013-07-30 | — | — | US | claimed |
| CN-103025160-A | Method for controlling sigatoka | NIHON NOHYAKU CO LTD | 2013-04-03 | — | — | CN | claimed |
| CN-102341393-A | Method of preparing (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | SUNESIS PHARMACEUTICAL INC | 2012-02-01 | — | — | CN | claimed |
| EP-2382214-A1 | METHOD OF PREPARING (+)-1,4-DIHYDRO-7-Ý(3S,4S)-3METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL¨-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | Sunesis Pharmaceuticals, Inc. (US) | 2011-11-02 | — | — | EP | claimed |
| US-20100203162-A1 | Method of preparing (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid | SUNESIS PHARMACEUTICALS, INC. | 2010-08-12 | — | — | US | claimed |
| WO-2010078294-A1 | METHOD OF PREPARING (+)-1,4-DIHYDRO-7-[(3S,4S)-3METHOXY-4-(METHYLAMINO)-1-PYRROLIDINYL]-4-OXO-1-(2-THIAZOLYL)-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID | SUNESIS PHARMACEUTICAL, INC. (US) | 2010-07-08 | — | — | WO | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| US-3956340-A | Process for the production of polyhalogenated nicotinic acids | CIBA-GEIGY CORPORATION (US) | 1976-05-11 | — | — | US | claimed |