Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29375536 | 1.00 | SLC6A12 (0.38) | SLC6A12NAPRTALDH1A1ALOX15KEAP1 | |
| SCHEMBL56617 | 0.82 | SMN1; SMN2 (0.50) | SLC6A12NAPRTALDH1A1ALOX15KEAP1 | |
| SCHEMBL29378242 | 0.82 | SMN1; SMN2 (0.50) | SLC6A12NAPRTALDH1A1ALOX15KEAP1 | |
| SCHEMBL27417425 | 0.80 | KEAP1 (0.38) | SLC6A12NAPRTKEAP1NFE2L2EGFR | |
| Water SCHEMBL28081708 | 0.80 | SMN1; SMN2 (0.48) | SLC6A12NAPRTALDH1A1ALOX15KEAP1 | |
| SCHEMBL28786268 | 0.80 | ALDH1A1 (0.37) | NAPRTALDH1A1ALOX15TUBB4ATUBB | |
| SCHEMBL3702546 | 0.80 | SMN1; SMN2 (0.40) | SLC6A12ALDH1A1KEAP1NFE2L2EGFR | |
| Hydrochloric Acid SCHEMBL2523036 | 0.80 | SMN1; SMN2 (0.48) | SLC6A12NAPRTALDH1A1ALOX15KEAP1 | |
| SCHEMBL30436565 | 0.80 | SMN1; SMN2 (0.40) | SLC6A12ALDH1A1KEAP1NFE2L2EGFR | |
| SCHEMBL893997 | 0.80 | KMT2A (0.42) | SLC6A12ALDH1A1GAALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 230 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117839460-A | Efficient magnesium-lithium separation nanofiltration membrane and preparation method and application thereof | 中国海洋大学 | 2024-04-09 | — | — | CN | claimed |
| CN-113004196-A | N- (benzyloxy) -2-chloronicotinamides compound and preparation method and application thereof | 浙江工业大学 | 2021-06-22 | — | — | CN | claimed |
| US-20260132127-A1 | NOVEL SPIRO COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2026-05-14 | — | — | US | disclosed |
| EP-4703365-A1 | QUINOLONE DERIVATIVE AND USE THEREOF AGAINST TUMORS | Horizon Omics Biotech Limited (CN) | 2026-03-04 | — | — | EP | disclosed |
| US-20260001861-A1 | PYRIDINE CARBOXAMIDE COMPOUNDS FOR INHIBITING NAV1.8 | LIEBER INST INC (US) | 2026-01-01 | — | — | US | disclosed |
| WO-2025242908-A2 | NOVEL COMPOUNDS | GENOME THERAPEUTICS LTD (GB) | 2025-11-27 | — | — | WO | disclosed |
| WO-2025133338-A1 | QUINOLONE DERIVATVES AGAINST CANCER | GENOME THERAPEUTICS LTD (GB) | 2025-06-26 | — | — | WO | disclosed |
| US-12234221-B2 | Pyridine carboxamide compounds for inhibiting NAV1.8 | LIEBER INSTITUTE, INC. (US) | 2025-02-25 | — | — | US | disclosed |
| WO-2025007784-A1 | HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION, PREPARATION METHOD THEREFOR AND USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2025-01-09 | — | — | WO | disclosed |
| WO-2024222630-A1 | QUINOLONE DERIVATIVE AND USE THEREOF AGAINST TUMORS | 信义核新(北京)生物科技有限公司 | 2024-10-31 | — | — | WO | disclosed |
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-5166352-A | Pyridinecarboxylic acid chlorides from (trichloromethyl)pyridines | DOWELANCO (US) | 1992-11-24 | — | — | US | disclosed |
| US-RE32975-E | FUNGICIDES, BACTERICIDES, FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1989-07-04 | — | — | US | disclosed |
| US-4753925-A | Antibacterial 1,7-diamino-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | disclosed |
| EP-0155587-B1 | 1,7-DIAMINO-1,4-DIHYDRO-4-OXO-3(AZA)QUINOLINE-CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN TREATING BACTERIAL DISEASES | BAYER AG (DE) | 1988-06-08 | — | — | EP | disclosed |
| EP-0155587-A1 | 1,7-Diamino-1,4-dihydro-4-oxo-3(aza)quinoline-carboxylic acids, process for their preparation and their use in treating bacterial diseases | BAYER AG (DE) | 1985-09-25 | — | — | EP | disclosed |
| EP-0004279-B1 | PROCESS FOR THE PREPARATION OF 4-PYRIDONE-3-CARBOXYLIC ACIDS, 1-CYCLOPROPYL-4-PYRIDONE-3-CARBOXYLIC ACID DERIVATIVES AND MEDICINES CONTAINING THEM | BAYER AG (DE) | 1982-12-29 | — | — | EP | disclosed |
| US-4284629-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1981-08-18 | — | — | US | disclosed |
| EP-0004279-A1 | Process for the preparation of 4-pyridone-3-carboxylic acids, 1-cyclopropyl-4-pyridone-3-carboxylic acid derivatives and medicines containing them | BAYER AG (DE) | 1979-10-03 | — | — | EP | disclosed |
| US-4089960-A | Antiemetic, psychosomatic and antipsychotic heterocyclic pyridine carboxamides | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | MERTK, DAPK1, AXL | SLC6A12 4745/4885NAPRT 431/4885ALDH1A1 1072/4885 |
| US-12234221-B2 | Pyridine carboxamide compounds for inhibiting NAV1.8 | SCN8A, SCN1A, SCN2A | SLC6A12 2281/4885NAPRT 187/4885ALDH1A1 2945/4885 |
| US-20260001861-A1 | PYRIDINE CARBOXAMIDE COMPOUNDS FOR INHIBITING NAV1.8 | SCN8A, SCN1A, SCN1B | SLC6A12 1443/4885NAPRT 1176/4885ALDH1A1 1730/4885 |
| US-20260132127-A1 | NOVEL SPIRO COMPOUND | TRHR, NR3C2, THRB | SLC6A12 681/4885NAPRT 3333/4885ALDH1A1 1063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.