Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.41 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL949255 | 0.84 | NCF1 (0.56) | MAPTKDM4ECYP3A4MEN1KMT2A | |
| SCHEMBL198641 | 0.76 | MAPT (0.64) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL11526779 | 0.76 | MAPT (0.62) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL217044 | 0.75 | MAPT (1.00) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL8384663 | 0.74 | MAPT (0.61) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL1282250 | 0.74 | MAPT (0.54) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL30123180 | 0.74 | MAPT (0.54) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL3967767 | 0.74 | MAPT (0.54) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL18848333 | 0.74 | KDM4E (0.48) | MAPTKDM4EPOLBCYP3A4LMNA | |
| SCHEMBL18434615 | 0.74 | MAPT (0.54) | MAPTKDM4EPOLBCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116496151-A | Method for preparing fluorenone derivative by using Catellani strategy | 长沙医学院 | 2023-07-28 | — | — | CN | claimed |
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2026-05-21 | — | — | US | disclosed |
| US-12565501-B2 | Muscarinic acetylcholine M1 receptor antagonists | CONTINEUM THERAPEUTICS, INC. (US) | 2026-03-03 | — | — | US | disclosed |
| WO-2025129168-A1 | TRIAZOLONE INHIBITORS OF NICOTINAMIDE N-METHYLTRANSFERASE AND THEIR THERAPEUTIC USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2025-06-19 | — | — | WO | disclosed |
| US-20250171455-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CONTINEUM THERAPEUTICS INC (US) | 2025-05-29 | — | — | US | disclosed |
| CN-119219602-A | 4-Lauryl-beta-lactam derivative and preparation method thereof | 苏州大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-119143673-A | 5-Aryl benzophenanthridine-6 (5H) -ketone C-N axis chiral compound and preparation method and application thereof | 浙江大学杭州国际科创中心 | 2024-12-17 | — | — | CN | disclosed |
| CN-118955428-A | Benzothiazinone vinylidene indene series compound with dibenzothiazepine octacycle system structure and preparation method thereof | 浙大城市学院 | 2024-11-15 | — | — | CN | disclosed |
| CN-116496151-B | Method for preparing fluorenone derivative by utilizing CATELLANI strategy | 长沙医学院 | 2024-08-23 | — | — | CN | disclosed |
| US-20230371357-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2023-11-16 | — | — | US | disclosed |
| EP-1276726-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | Abbott Laboratories (US) | 2003-01-22 | — | — | EP | disclosed |
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | ABBOTT LABORATORIES | 2002-02-14 | — | — | US | disclosed |
| WO-2001081316-A2 | SUBSTITUTED PHENYL FARNESYLTRANSFERASE INHIBITORS | ABBOTT LABORATORIES (US) | 2001-11-01 | — | — | WO | disclosed |
| US-6124460-A | Isoquinuclidine derivatives, method of manufacturing the same and therapeutic agents for hypercholesterolemia containing these compounds | KOTOBUKI PHARMACEUTICAL CO. LTD. (JP) | 2000-09-26 | — | — | US | disclosed |
| US-5776939-A | PIPERAZINE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1998-07-07 | — | — | US | disclosed |
| WO-1998022112-A1 | DRUG RESISTANCE AND MULTIDRUG RESISTANCE MODULATORS | ELI LILLY AND COMPANY (US) | 1998-05-28 | — | — | WO | disclosed |
| EP-0844244-A1 | Drug resistance and multidrug resistance modulators | ELI LILLY AND COMPANY (US) | 1998-05-27 | — | — | EP | disclosed |
| US-4052509-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4042699-A | 5-METHYL-1-PHENYL-2-(1H)-PYRIDONE | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1977-08-16 | — | — | US | disclosed |
| US-3974281-A | ANALGESICS, ANTI-PYRETIC AND ANTI-INFLAMMATORY AGENTS | AFFILIATED MEDICAL RESEARCH, INC. (US) | 1976-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230371357-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE | L1CAM, CHRM1, FOXM1 | MAPT 775/4885KDM4E 3285/4885POLB 2882/4885 |
| US-12565501-B2 | Muscarinic acetylcholine M1 receptor antagonists | CHRM1, CHRM2, CHRM3 | MAPT 1855/4885KDM4E 3624/4885POLB 3431/4885 |
| US-20260138987-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM5, CHRM3 | MAPT 2127/4885KDM4E 3909/4885POLB 3691/4885 |
| US-20020019527-A1 | Substituted phenyl farnesyltransferase inhibitors | FNTA, FNTB, SLC10A1 | MAPT 1802/4885KDM4E 3715/4885POLB 3455/4885 |
| US-20250171455-A1 | MUSCARINIC ACETYLCHOLINE M1 RECEPTOR ANTAGONISTS | CHRM1, CHRM2, CHRM3 | MAPT 458/4885KDM4E 3057/4885POLB 4007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.