SCHEMBL949255

SCHEMBL949255

Ic1ccnc2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 2/20 0.56
LOXL2 Q9Y4K0 1/20 0.52
HTR1A P08908 2/20 0.48
ADRA1D P25100 2/20 0.48
ADRA1A P35348 2/20 0.48
ADRA1B P35368 2/20 0.48
KDM4E B2RXH2 4/20 0.48
MAPT P10636 3/20 0.48
CYP3A4 P08684 1/20 0.43
ALDH1A1 P00352 3/20 0.43
CYP1A2 P05177 2/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
HPGD P15428 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MAPK1 P28482 2/20 0.43
TP53 P04637 1/20 0.43
PTK2B Q14289 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
FERMT2 Q96AC1 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL566334 0.84 MAPT (0.58) NCF1LOXL2KDM4EMAPTCYP3A4
SCHEMBL20019491 0.80 KDM4E (0.42) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL28341049 0.76 LMNA (0.56) NCF1HTR1AKDM4EMAPTCYP3A4
SCHEMBL27917128 0.75 CYP1A2 (0.60) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL1227713 0.75 CYP1A2 (0.60) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL29699887 0.75 CYP1A2 (0.60) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL30487734 0.73 CYP1A2 (0.58) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL134737 0.73 NCF1 (0.58) NCF1LOXL2HTR1AADRA1DADRA1A
SCHEMBL18574397 0.73 CCNC (0.39) NCF1KDM4EMAPT
SCHEMBL17059461 0.73 PARP1 (0.47) NCF1LOXL2HTR1AADRA1DADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11242957-B2 Kinetic hydrate inhibitors for controlling gas hydrate formation in wet gas systems CHAMPIONX USA INC. (US) 2022-02-08 US claimed
CN-108530241-B Preparation method of benzo ring derivative with benzyl quaternary carbon center 武汉大学 2021-02-02 CN claimed
US-20190353307-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS HARBISON-FISCHER, INC. 2019-11-21 US claimed
EP-3420055-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS Ecolab USA Inc. (US) 2019-01-02 EP claimed
WO-2017147426-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS ECOLAB USA INC. (US) 2017-08-31 WO claimed
US-20170248276-A1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS US SYNTHETIC CORPORATION 2017-08-31 US claimed
CN-1250540-C Improved single-reactor synthesis of [2,8-di(trifluoromethyl)-4-quinolyl]-2-pyridyl methyl ketone and methylfluoro quine NAT PHARMACEUTICAL EDUCATION A (IN) 2006-04-12 CN claimed
CN-1370777-A Improved single-reactor synthesis of [2,8-di(trifluoromethyl)-4-quinolyl]-2-pyridyl methyl ketone and methylfluoro quine NAT PHARMACEUTICAL EDUCATION A (IN) 2002-09-25 CN claimed
EP-3420055-B1 KINETIC HYDRATE INHIBITORS FOR CONTROLLING GAS HYDRATE FORMATION IN WET GAS SYSTEMS CHAMPIONX LLC (US) 2025-04-09 EP disclosed
EP-4063368-B1 NITROGEN-CONTAINING COMPOUND AND ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MAT CO LTD (CN) 2024-06-26 EP disclosed
EP-4328285-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND DEVICE THEREOF Beijing Summer Sprout Technology Co., Ltd. (CN) 2024-02-28 EP disclosed
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-01-18 US disclosed
CN-114213441-B Boron or phosphorus fused ring compound, preparation method thereof and light-emitting device 中国科学院长春应用化学研究所 2023-12-01 CN disclosed
US-11825740-B2 Amine compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2023-11-21 US disclosed
EP-2139880-A1 QUINOLINE COMPOUNDS SUITABLE FOR TREATING DIDORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR Abbott GmbH & Co. KG (DE) 2010-01-06 EP disclosed
WO-2009062285-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-05-22 WO disclosed
WO-2009062289-A1 INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2009-05-22 WO disclosed
WO-2009019286-A1 QUINOLINE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2009-02-12 WO disclosed
WO-2008116831-A1 QUINOLINE COMPOUNDS SUITABLE FOR TREATING DIDORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR ABBOTT GMBH & CO. KG (DE) 2008-10-02 WO disclosed
US-20020019527-A1 Substituted phenyl farnesyltransferase inhibitors ABBOTT LABORATORIES 2002-02-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018175-A1 ORGANOMETALLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS AND ELECTRONIC EQUIPMENT INCLUDING THE LIGHT-EMITTING DEVICE GPX1, LAGE3, NFE2L2 NCF1 1350/4885LOXL2 571/4885HTR1A 3903/4885
US-20020019527-A1 Substituted phenyl farnesyltransferase inhibitors FNTA, FNTB, SLC10A1 NCF1 1174/4885LOXL2 3142/4885HTR1A 4058/4885
US-11825740-B2 Amine compound and organic light-emitting device including the same AOC2, AOC1, AOC3 NCF1 2107/4885LOXL2 112/4885HTR1A 29/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.