SCHEMBL5664258

SCHEMBL5664258

C=C(C)c1cccc(C(C)(C)[NH])c1

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.48
TSHR P16473 2/20 0.47
HTT P42858 2/20 0.47
MAPT P10636 2/20 0.47
LMNA P02545 1/20 0.47
ALDH1A1 P00352 3/20 0.44
KDM4E B2RXH2 1/20 0.44
POLB P06746 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18408453 0.84 ACHE (0.55) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL4880904 0.82 L3MBTL1 (0.49) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL3253267 0.81 L3MBTL1 (0.48) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL1304921 0.81 L3MBTL1 (0.48) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL8680645 0.81 L3MBTL1 (0.48) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL20219995 0.81 L3MBTL1 (0.48) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL1707006 0.79 L3MBTL1 (0.47) L3MBTL1TSHRHTTMAPTLMNA
SCHEMBL30106109 0.78 CES2 (0.60) LMNAALDH1A1POLB
SCHEMBL32016 0.78 CES2 (0.60) LMNAALDH1A1POLB
SCHEMBL13484002 0.78 L3MBTL1 (0.46) L3MBTL1TSHRHTTMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0127802-A2 Meta- and para-isopropenyl-alpha,alpha-dimethylbenzylamine AMERICAN CYANAMID COMPANY (US) 1984-12-12 EP claimed
US-6987174-B2 Azo compound, colorant-containing curable composition, color filter and color filter production method FUJI PHOTO FILM CO., LTD. (JP) 2006-01-17 US disclosed
US-20040260075-A1 Azo compound, colorant-containing curable composition, color filter and color filter production method FUJI PHOTO FILM CO., LTD. 2004-12-23 US disclosed