Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.52 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.52 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.52 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.52 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.52 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | ARAF | P10398 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL258010 | 0.89 | BRAF (0.58) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL1558756 | 0.79 | BRAF (0.65) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL655826 | 0.79 | ALDH1A1 (0.53) | POLBMAPTHTTNPSR1SMN1; SMN2 | |
| SCHEMBL25501013 | 0.77 | KDR (0.51) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| Hydrochloric Acid SCHEMBL2553196 | 0.77 | ALDH1A1 (0.51) | KDM4EPOLBMAPTHTTNPSR1 | |
| SCHEMBL257948 | 0.77 | MMP13 (0.59) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL31557926 | 0.77 | BRAF (0.61) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL14193085 | 0.77 | BRAF (0.61) | BRAFHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6589289 | 0.77 | GAA (0.51) | KDM4EPOLBALDH1A1MEN1KMT2A | |
| SCHEMBL5149668 | 0.76 | BRAF (0.49) | BRAFHDAC1HDAC3HDAC4HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235576-B1 | Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors | BAYER PHARMACEUTICALS CORPORATION (US) | 2007-06-26 | — | — | US | disclosed |