SCHEMBL5664732

SCHEMBL5664732

CCOc1c[c]ccc1N(C)C

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.33
NQO1 P15559 1/20 0.32
KDM4E B2RXH2 4/20 0.32
L3MBTL1 Q9Y468 3/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
MAPK1 P28482 1/20 0.32
HSD17B10 Q99714 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27675673 0.85 ALDH1A1 (0.33) ALDH1A1NQO1KDM4EL3MBTL1KMT2A
SCHEMBL3209325 0.79 APP (0.40)
SCHEMBL127280 0.78 ALDH1A1 (0.39) ALDH1A1NQO1KDM4EL3MBTL1KMT2A
SCHEMBL10458094 0.76 ALDH1A1 (0.38) ALDH1A1NQO1KDM4EL3MBTL1KMT2A
SCHEMBL16956175 0.74 MAPT (0.35) ALDH1A1NQO1KDM4EL3MBTL1KMT2A
SCHEMBL596640 0.73 L3MBTL1 (0.37) ALDH1A1NQO1KDM4EL3MBTL1KMT2A
SCHEMBL159256 0.73 KDM4E (0.42) ALDH1A1KDM4EMAPTMAPK1SMN1; SMN2
SCHEMBL5400824 0.73 ALDH1A1 (0.53) ALDH1A1NQO1KDM4EL3MBTL1KMT2A
SCHEMBL182827 0.73 MAPT (0.46) ALDH1A1KDM4EL3MBTL1KMT2AMAPT
SCHEMBL160145 0.73 L3MBTL1 (0.46) ALDH1A1NQO1KDM4EL3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060205594-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2006-09-14 US disclosed