Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6584974 | 0.83 | APP (0.40) | APPCA1CA2CA12CA4 | |
| SCHEMBL8527133 | 0.79 | HTT (0.30) | — | |
| SCHEMBL5664732 | 0.79 | ALDH1A1 (0.33) | — | |
| SCHEMBL2776293 | 0.75 | KDM4E (0.32) | — | |
| SCHEMBL8674 | 0.75 | CA2 (0.46) | CA1CA2CA12CA4CA7 | |
| SCHEMBL27588573 | 0.73 | HTR7 (0.44) | APPCA1CA2CA12CA4 | |
| SCHEMBL6541679 | 0.73 | CA1 (0.38) | APPCA1CA2CA12CA4 | |
| SCHEMBL96297 | 0.73 | — | — | |
| SCHEMBL27494520 | 0.73 | CA2 (0.43) | CA1CA2CA12CA4CA7 | |
| SCHEMBL28251730 | 0.73 | CA2 (0.43) | CA1CA2CA12CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PHARMA EIGHT CO., LTD. (JP) | 2014-03-27 | — | — | US | claimed |
| EP-2698368-A1 | NOVEL PYRAZOLE DERIVATIVE | Pharma Eight Co. Ltd (JP) | 2014-02-19 | — | — | EP | claimed |
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2010-02-25 | — | — | US | claimed |
| US-11760819-B2 | Ethylene α-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof | MITSUI CHEMICALS, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
| EP-3272790-B1 | THERMOPLASTIC ELASTOMER COMPOSITION, USE THEREOF, METHOD FOR PRODUCING SAME, ETHYLENE/ -OLEFIN/UNCONJUGATED POLYENE COPOLYMER AND USE THEREOF | MITSUI CHEMICALS INC (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-11613595-B2 | Ethylene alpha-olefin non-conjugated polyene copolymer, use thereof, and manufacturing method thereof | MITSUI CHEMICALS, INC. (JP) | 2023-03-28 | — | — | US | disclosed |
| CN-109824809-B | Ethylene-alpha-olefin-nonconjugated polyene copolymer and use thereof | 三井化学株式会社 | 2022-06-28 | — | — | CN | disclosed |
| CN-107428956-B | Thermoplastic elastomer composition, use thereof, process for producing the same, ethylene-alpha-olefin-nonconjugated polyene copolymer, and use thereof | 三井化学株式会社 | 2022-05-17 | — | — | CN | disclosed |
| EP-3106480-B1 | ETHYLENE/A-OLEFIN/NON-CONJUGATED POLYENE COPOLYMER, USE THEREFOR, AND MANUFACTURING METHOD THEREFOR | MITSUI CHEMICALS INC (JP) | 2022-04-06 | — | — | EP | disclosed |
| EP-3272805-B1 | THERMOPLASTIC ELASTOMER COMPOSITION AND METHOD FOR PRODUCING SAME | MITSUI CHEMICALS INC (JP) | 2021-08-11 | — | — | EP | disclosed |
| US-11078352-B2 | Thermoplastic elastomer composition, use thereof, method for producing same, ethylene/α-olefin/unconjugated polyene copolymer and use thereof | MITSUI CHEMICALS, INC. (JP) | 2021-08-03 | — | — | US | disclosed |
| EP-0365089-A2 | 2-Aryl-5(3-methoxy-5-(hydroxypropylsulfonyl)-4-propoxyphenyl) tetrahydrothiophen and analogs | MERCK & CO. INC. (US) | 1990-04-25 | — | — | EP | disclosed |
| EP-0144804-B1 | NEW 2,5-DIARYL TETRAHYDROFURANS AND ANALOGS THEREOF AS PAF-ANTAGONISTS | MERCK & CO. INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0154887-B1 | NEW 2,5-DIARYL TETRAHYDROTHIOPHENES AND ANALOGS THEREOF AS PAF-ANTAGONISTS | MERCK & CO. INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0257921-A2 | New 1,3-diaryl cyclopentanes and derivatives thereof as paf antagonists | MERCK & CO. INC. (US) | 1988-03-02 | — | — | EP | disclosed |
| EP-0199324-A2 | New 2,5-diaryl tetryhydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1986-10-29 | — | — | EP | disclosed |
| US-4595693-A | Method of use of 2,5-diaryl tetrahydrofurans and analogs thereof as PAF-antagonists | MERCK & CO., INC. (US) | 1986-06-17 | — | — | US | disclosed |
| EP-0154887-A1 | New 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists | MERCK & CO. INC. (US) | 1985-09-18 | — | — | EP | disclosed |
| US-4539332-A | PLATELET ACTIVATION FACTOR | MERCK & CO., INC. (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0144804-A2 | New 2,5-diaryl tetrahydrofurans and analogs thereof as paf-antagonists | MERCK & CO. INC. (US) | 1985-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048901-A1 | NOVEL CURCUMIN DERIVATIVE | BACE1, APP, BACE2 | APP 2/4885CA1 271/4885CA2 1240/4885 |
| US-20140088029-A1 | NOVEL PYRAZOLE DERIVATIVE | PSEN2, MAPT, PSEN1 | APP 4/4885CA1 2918/4885CA2 3260/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.