SCHEMBL472296

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL566522	0.91	CA1 (0.35)	PDK1PDK2PDK3PDK4MEN1
	SCHEMBL1547703	0.90	LMNA (0.36)	CHUKMEN1KMT2ALMNACA1
	SCHEMBL472622	0.90	CA1 (0.33)	CHUKMEN1KMT2ACA1CA2
	SCHEMBL10039281	0.90	RAB9A (0.40)	PDK1PDK2PDK3PDK4MEN1
	SCHEMBL1547842	0.88	CA1 (0.35)	PDK1PDK2PDK3PDK4CA1
	SCHEMBL13299438	0.87	MEN1 (0.34)	MEN1KMT2ALMNACA1CA2
	SCHEMBL1611856	0.87	MEN1 (0.42)	PDK1PDK2PDK3PDK4CHUK
	SCHEMBL10039199	0.87	MEN1 (0.45)	MEN1KMT2ARAB9ATP53NPC1
	SCHEMBL10039214	0.86	HSP90AA1 (0.34)	PDK1PDK2PDK3PDK4CA1
	SCHEMBL472769	0.85	CA1 (0.34)	PDK1PDK2PDK3PDK4MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.