SCHEMBL5666176

SCHEMBL5666176

C=CCc1c(N)cc(N)c(N)c1CC=C

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.36
NPSR1 Q6W5P4 1/20 0.31
PTK2 Q05397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10708328 0.83 GABRA1 (0.34) IMPDH2
SCHEMBL9244533 0.83 GABRA1 (0.34) IMPDH2
SCHEMBL5984000 0.78 GABRA1 (0.34) IMPDH2
SCHEMBL28716719 0.77 NPSR1 (0.38) IMPDH2NPSR1
SCHEMBL5135211 0.76 GABRA1 (0.35) IMPDH2NPSR1
SCHEMBL845635 0.75 IMPDH2 (0.53) IMPDH2NPSR1
SCHEMBL473069 0.74 IMPDH2 (0.34) IMPDH2
SCHEMBL28809380 0.74 IMPDH2 (0.32) IMPDH2
SCHEMBL9014962 0.73 XDH (0.38) IMPDH2NPSR1
SCHEMBL3423968 0.72 NPSR1 (0.35) IMPDH2NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1155353-B1 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS ELSICON INC (US) 2006-10-04 EP disclosed
EP-1155353-A4 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS ELSICON INC (US) 2003-04-23 EP disclosed
EP-1155353-A1 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS Elsicon Inc. (US) 2001-11-21 EP disclosed
WO-2000039633-A1 MATERIALS FOR INDUCING ALIGNMENT OF LIQUID CRYSTALS AND LIQUID CRYSTAL OPTICAL ELEMENTS ELSICON, INC. (US) 2000-07-06 WO disclosed