SCHEMBL5666512

SCHEMBL5666512

O=C(O)c1ccc(C(=O)O)c(-c2ccccc2C#Cc2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.44
XDH P47989 1/20 0.41
SLC22A12 Q96S37 1/20 0.41
HNF4A P41235 2/20 0.40
ACMSD Q8TDX5 2/20 0.39
TTR P02766 1/20 0.39
FFAR1 O14842 1/20 0.39
DCLRE1A Q6PJP8 1/20 0.39
DCLRE1B Q9H816 1/20 0.39
SLC16A3 O15427 1/20 0.39
PTPRC P08575 2/20 0.38
KDM4E B2RXH2 1/20 0.38
DDT P30046 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27503029 0.90 FFAR1 (0.46) KMOHNF4AACMSDTTRFFAR1
SCHEMBL5667272 0.90 NPC1 (0.46) HNF4ATTRFFAR1SLC16A3PTPRC
SCHEMBL5667422 0.87 TTR (0.45) KMOHNF4ATTRFFAR1PTPRC
SCHEMBL5667285 0.85 KMO (0.50) KMOXDHSLC22A12HNF4AACMSD
SCHEMBL5667919 0.84 DDT (0.49) KMOXDHSLC22A12HNF4ATTR
SCHEMBL5667268 0.82 DHODH (0.49) KMOFFAR1SLC16A3NPC1RAB9A
SCHEMBL5667928 0.81 KMO (0.47) KMOHNF4AACMSDTTRDCLRE1A
SCHEMBL5667719 0.80 KMO (0.41) KMOXDHSLC22A12HNF4AACMSD
SCHEMBL5669452 0.77 KDM4E (0.45) KMOHNF4AACMSDTTRFFAR1
SCHEMBL27827385 0.76 KMO (0.65) KMOHNF4AACMSDTTRDCLRE1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed