SCHEMBL5669452

SCHEMBL5669452

O=C(O)c1ccc(C(=O)O)c(C#Cc2ccccc2-c2ccccc2)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
FFAR1 O14842 1/20 0.45
ALDH1A1 P00352 1/20 0.43
HNF4A P41235 2/20 0.42
TTR P02766 1/20 0.42
PTPRC P08575 2/20 0.41
KMO O15229 1/20 0.41
PTPN1 P18031 1/20 0.41
SRD5A2 P31213 2/20 0.40
FABP3 P05413 1/20 0.40
FABP4 P15090 1/20 0.40
FABP5 Q01469 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
SRD5A1 P18405 1/20 0.40
CDC25B P30305 2/20 0.39
CDC25A P30304 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ATM Q13315 1/20 0.39
ACMSD Q8TDX5 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667422 0.90 TTR (0.45) KDM4EFFAR1ALDH1A1HNF4ATTR
SCHEMBL5667821 0.83 RXRA (0.41) KDM4EFFAR1ALDH1A1HNF4ATTR
SCHEMBL27503365 0.82 HNF4A (0.46) KDM4EALDH1A1HNF4AKMOCDC25B
SCHEMBL5667454 0.81 FFAR1 (0.49) FFAR1ALDH1A1HNF4ATTRPTPRC
SCHEMBL1713039 0.81 HNF4A (0.51) KDM4EFFAR1HNF4ATTRPTPN1
SCHEMBL5666618 0.80 FFAR1 (0.41) KDM4EFFAR1ALDH1A1TTRPTPRC
SCHEMBL5667285 0.79 KMO (0.50) KDM4EHNF4AKMOCDC25BATM
SCHEMBL27503029 0.79 FFAR1 (0.46) KDM4EFFAR1ALDH1A1HNF4ATTR
SCHEMBL5667058 0.78 FFAR1 (0.40) KDM4EFFAR1ALDH1A1TTRPTPRC
SCHEMBL3137844 0.78 HSD17B10 (0.52) KDM4EALDH1A1PTPN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed