SCHEMBL5667285

SCHEMBL5667285

O=C(O)c1ccc(C(=O)O)c(C#Cc2cccc(-c3ccccc3)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.50
XDH P47989 1/20 0.46
SLC22A12 Q96S37 1/20 0.46
HNF4A P41235 3/20 0.44
ACMSD Q8TDX5 3/20 0.44
DCLRE1A Q6PJP8 1/20 0.43
DCLRE1B Q9H816 1/20 0.43
KDM4E B2RXH2 1/20 0.43
DHFR P00374 1/20 0.41
MCL1 Q07820 1/20 0.41
CDC25B P30305 1/20 0.41
ATM Q13315 1/20 0.41
TRIM24 O15164 1/20 0.40
TRIM33 Q9UPN9 1/20 0.40
DHODH Q02127 1/20 0.40
SLC16A3 O15427 1/20 0.40
EGFR P00533 1/20 0.40
IP6K1 Q92551 1/20 0.39
IP6K3 Q96PC2 1/20 0.39
IP6K2 Q9UHH9 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27503365 0.88 HNF4A (0.46) KMOHNF4AACMSDDCLRE1ADCLRE1B
SCHEMBL1713039 0.88 HNF4A (0.51) HNF4AKDM4ECDC25BSLC16A3
SCHEMBL5666512 0.85 KMO (0.44) KMOXDHSLC22A12HNF4AACMSD
SCHEMBL2254192 0.83 BCL2L1 (0.51) XDHSLC22A12HNF4AACMSDDCLRE1A
SCHEMBL5667719 0.82 KMO (0.41) KMOXDHSLC22A12HNF4AACMSD
SCHEMBL5668905 0.81 KMO (0.45) KMOTRIM24TRIM33DHODHSLC16A3
SCHEMBL5667919 0.81 DDT (0.49) KMOXDHSLC22A12HNF4AKDM4E
SCHEMBL5667656 0.80 HNF4A (0.53) XDHSLC22A12HNF4AACMSDDCLRE1A
SCHEMBL5669452 0.79 KDM4E (0.45) KMOHNF4AACMSDKDM4ECDC25B
SCHEMBL5669165 0.79 PTPN1 (0.49) KMOXDHSLC22A12HNF4AACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed