SCHEMBL5669133

SCHEMBL5669133

O=C(O)c1cccc(C(=O)O)c1C#Cc1cccc(-c2ccccc2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 3/20 0.50
XDH P47989 1/20 0.48
SLC22A12 Q96S37 1/20 0.48
ACMSD Q8TDX5 3/20 0.47
DHFR P00374 1/20 0.46
MCL1 Q07820 1/20 0.46
MGLL Q99685 1/20 0.46
PTPN6 P29350 5/20 0.46
PTPN11 Q06124 5/20 0.46
PTPN22 Q9Y2R2 5/20 0.46
PTPRC P08575 4/20 0.46
PTPN2 P17706 4/20 0.46
PTPN1 P18031 4/20 0.46
PTPN9 P43378 4/20 0.46
DUSP3 P51452 4/20 0.46
KMO O15229 1/20 0.44
PTGES O14684 1/20 0.43
AKR1C2 P52895 2/20 0.43
AKR1C1 Q04828 2/20 0.43
EPM2A O95278 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5668837 0.86 HNF4A (0.49) HNF4AACMSDDHFRMCL1PTPN6
SCHEMBL5669824 0.86 HNF4A (0.41) HNF4AXDHSLC22A12ACMSDDHFR
SCHEMBL1713009 0.86 HNF4A (0.55) HNF4APTPN6PTPN11PTPN22PTPRC
SCHEMBL5669173 0.84 PTPN11 (0.43) HNF4AXDHSLC22A12ACMSDDHFR
SCHEMBL5667085 0.81 NPC1 (0.46) HNF4AXDHSLC22A12ACMSDDHFR
SCHEMBL5669165 0.80 PTPN1 (0.49) HNF4AXDHSLC22A12ACMSDPTPN6
SCHEMBL5667352 0.77 HNF4A (0.50) HNF4APTPN6PTPN11PTPN22PTPRC
SCHEMBL5667285 0.77 KMO (0.50) HNF4AXDHSLC22A12ACMSDDHFR
SCHEMBL5667762 0.77 BCL2 (0.49) KMO
SCHEMBL5666602 0.76 HNF4A (0.40) HNF4AXDHSLC22A12ACMSDDHFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed