Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.60 |
| ▸ | PRKCG | P05129 | 5/20 | 0.60 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.60 |
| ▸ | PRKCB | P05771 | 4/20 | 0.60 |
| ▸ | PRKCH | P24723 | 4/20 | 0.60 |
| ▸ | PRKCI | P41743 | 4/20 | 0.60 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.60 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.60 |
| ▸ | PRKCZ | Q05513 | 4/20 | 0.60 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.60 |
| ▸ | PRKD1 | Q15139 | 4/20 | 0.60 |
| ▸ | VAV1 | P15498 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phorbol SCHEMBL15976176 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL2329457 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL1733926 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL3403135 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL12950512 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL14937 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL8190878 | 1.00 | PRKCA (0.60) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL23880303 | 0.99 | PRKCA (0.59) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL5310296 | 0.99 | PRKCA (0.59) | PRKCAPRKCGPRKD3PRKCBPRKCH | |
| Phorbol SCHEMBL19435231 | 0.98 | PRKCA (0.59) | PRKCAPRKCGPRKD3PRKCBPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1226269-B1 | ASSAY | GENENTECH INC (US) | 2003-06-18 | — | — | EP | claimed |
| EP-0108919-B1 | PROCESS FOR PRODUCING T CELL-ACTIVATING FACTOR | Okai, Yasuji (JP) | 1988-07-13 | — | — | EP | claimed |
| CN-113350355-B | Application of GSK923295 and Istexus as recombinant tPA agonist in preparation of thrombolytic drugs | 福州大学 | 2023-03-03 | — | — | CN | disclosed |
| EP-4117723-A1 | COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE | Oxford University Innovation Limited (GB) | 2023-01-18 | — | — | EP | disclosed |
| WO-2022084663-A1 | COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE | THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD (GB) | 2022-04-28 | — | — | WO | disclosed |
| WO-2021181100-A1 | COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2021-09-16 | — | — | WO | disclosed |
| WO-2018215766-A1 | COMPOSITIONS AND METHODS FOR INDUCING AN IMMUNE RESPONSE | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2018-11-29 | — | — | WO | disclosed |
| US-20160133152-A1 | SYSTEM AND METHOD FOR COACH DECISION SUPPORT | UMM AL-QURA UNIVERSITY (SA) | 2016-05-12 | — | — | US | disclosed |
| EP-1626735-A2 | COMPOUND AND METHOD FOR REGULATING PLASMINOGEN ACTIVATION AND CELL MIGRATION | Transfert Plus (CA) | 2006-02-22 | — | — | EP | disclosed |
| WO-2004099410-A2 | COMPOUND AND METHOD FOR REGULATING PLASMINOGEN ACTIVATION AND CELL MIGRATION | TRANSFERT PLUS (CA) | 2004-11-18 | — | — | WO | disclosed |
| US-6056958-A | Method of treatment of arterial and venous thromboembolic disorders | DUPONT PHARMACEUTICALS (US) | 2000-05-02 | — | — | US | disclosed |
| WO-1998032459-A1 | PLASMINOGEN ACTIVATOR AS AN ANTI-INFLAMMATORY AGENT | UNIVERSITY TECHNOLOGY CORPORATION (US) | 1998-07-30 | — | — | WO | disclosed |
| US-5227297-A | Affinity purification ligands | SMITHKLINE BEECHAM CORPORATION (US) | 1993-07-13 | — | — | US | disclosed |
| US-5141862-A | Immobilization on solid support | SMITHKLINE BEECHAM CORPORATION (US) | 1992-08-25 | — | — | US | disclosed |
| WO-1989009820-A1 | PURIFIED TYPE I AND TYPE II tPA | INVITRON CORPORATION (US) | 1989-10-19 | — | — | WO | disclosed |