SCHEMBL5668188

SCHEMBL5668188

C#Cc1ccc(-c2ccc(C#C)c(C(=O)O)c2)cc1C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
KDM4E B2RXH2 1/20 0.50
GFER P55789 1/20 0.50
RXFP1 Q9HBX9 1/20 0.50
ACMSD Q8TDX5 6/20 0.46
MCL1 Q07820 5/20 0.46
HNF4A P41235 2/20 0.46
DHFR P00374 1/20 0.46
LCK P06239 2/20 0.43
CFD P00746 1/20 0.43
KEAP1 Q14145 1/20 0.40
NFE2L2 Q16236 1/20 0.40
PTPN1 P18031 1/20 0.39
MEN1 O00255 1/20 0.38
APP P05067 1/20 0.38
THRB P10828 1/20 0.38
RECQL P46063 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667262 0.83 ACMSD (0.46) KMT2AKDM4EGFERRXFP1ACMSD
SCHEMBL689828 0.82 HNF4A (0.41) KMT2AHNF4AKEAP1NFE2L2MEN1
SCHEMBL5006696 0.82 KDM4E (0.47) KDM4EPTPN1TDP1HSD17B10
Benzene SCHEMBL28354744 0.79 CSNK2A1 (0.53) KMT2AKDM4EGFERMCL1MEN1
Benzene SCHEMBL28354519 0.79 KDM4E (0.52) KMT2AKDM4ERXFP1MEN1TDP1
SCHEMBL402519 0.78 ALDH1A1 (0.50) KDM4EACMSDMCL1HNF4ADHFR
SCHEMBL1095325 0.77 ACMSD (0.58) ACMSDMCL1HNF4ADHFRPTPN1
SCHEMBL1927621 0.77 ACMSD (0.50) KMT2AACMSDMCL1HNF4ADHFR
Hydrochloric Acid SCHEMBL2707920 0.76 ALDH1A1 (0.48) KDM4EACMSDMCL1HNF4ADHFR
Hydrochloric Acid SCHEMBL4352423 0.76 ACMSD (0.56) ACMSDMCL1HNF4ADHFRPTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed
EP-1327653-A1 HEAT-RESISTANT RESIN PRECURSOR, HEAT-RESISTANT RESIN AND INSULATING FILM AND SEMICONDUCTOR DEVICE SUMITOMO BAKELITE CO., LTD. (JP) 2003-07-16 EP disclosed
US-6518390-B2 Polybenzoxazole and crosslinking agent SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-02-11 US disclosed
US-20020013443-A1 Precursor of a heat resistant resin, heat resistant resin, insulating film and semiconductor device SUMITOMO BAKELITE CO., LTD. (JP) 2002-01-31 US disclosed