Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.30 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28648336 | 0.72 | CA5A (0.55) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| SCHEMBL10453205 | 0.71 | LAP3 (0.38) | TDP1ANPEPLAP3 | |
| Phosphoric Acid SCHEMBL28087205 | 0.68 | CA5A (0.60) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL11396439 | 0.68 | CA5A (0.60) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL10954820 | 0.68 | CA5A (0.60) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL241917 | 0.68 | CA5A (0.60) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL8214768 | 0.68 | CA5A (0.60) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL25306181 | 0.65 | CA5A (0.55) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL5144798 | 0.65 | CA5A (0.55) | MMP2KDM4ETHRBMAPK1HSD17B10 | |
| Phosphoric Acid SCHEMBL10534634 | 0.65 | CA5A (0.55) | MMP2KDM4ETHRBMAPK1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1157566-A | Phosphonates and parathyroid hormone for osteoporosis | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | claimed |
| CN-1157565-A | Method for treatment of osteoporosis using bone active phosphonates and parathyroid hormone | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | claimed |
| US-20060189567-A1 | Compound having affinity with calcified tissue | NIHON MEDI-PHYSICS CO., LTD. (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1609797-A1 | COMPOUND HAVING AFFINITY WITH CALCIFIED TISSUE | Nihon Medi-Physics Co., Ltd. (JP) | 2005-12-28 | — | — | EP | disclosed |
| CN-1157565-A | Method for treatment of osteoporosis using bone active phosphonates and parathyroid hormone | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | disclosed |
| CN-1157566-A | Phosphonates and parathyroid hormone for osteoporosis | PROCTER & GAMBLE (US) | 1997-08-20 | — | — | CN | disclosed |
| US-4810486-A | FROM SULFONATE-CONTAINING BIS-PHOSPHONIC ACID, REDUCING AGENT, PERTECHNEATATE IONS | AMERSHAM INTERNATIONAL PLC. (GB) | 1989-03-07 | — | — | US | disclosed |
| EP-0270648-A1 | BONE-SEEKING COMPLEXES OF TECHNETIUM-99m | AMERSHAM INTERNATIONAL plc (GB) | 1988-06-15 | — | — | EP | disclosed |
| WO-1988000061-A1 | BONE-SEEKING COMPLEXES OF TECHNETIUM-99m | AMERSHAM INTERNATIONAL PLC (GB) | 1988-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189567-A1 | Compound having affinity with calcified tissue | SLC7A1, MBNL1, SHBG | MMP2 1805/4885CA12 36/4885CA14 34/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.