SCHEMBL566977

SCHEMBL566977

C/C(=C/C(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
MAPK1 P28482 2/20 0.54
ALDH1A1 P00352 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC3 O15379 1/20 0.53
NCOR2 Q9Y618 1/20 0.53
AKT1 P31749 1/20 0.52
MAPT P10636 4/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
GAA P10253 2/20 0.51
THRB P10828 1/20 0.51
DEGS1 O15121 1/20 0.51
RECQL P46063 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133764 1.00 NFE2L2 (0.61) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL566978 1.00 NFE2L2 (0.61) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL23086309 0.90 CES2 (0.57) NFE2L2MEN1KMT2AALDH1A1TDP1
SCHEMBL23086307 0.90 CES2 (0.57) NFE2L2MEN1KMT2AALDH1A1TDP1
SCHEMBL17129921 0.88 NFE2L2 (0.53) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL15080850 0.88 NFE2L2 (0.53) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL17129920 0.86 NFE2L2 (0.52) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL12720046 0.86 MEN1 (0.47) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL566675 0.84 NFE2L2 (0.64) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL566351 0.84 DEGS1 (0.53) NFE2L2MEN1KMT2AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115650837-A Method for preparing ketone compound by utilizing 1,4 addition reaction of alpha, beta unsaturated ketene 南京工业大学 2023-01-31 CN claimed
CN-113004169-A Preparation method of 1, 3-diphenyl-2-butene-1-one O-n-butyl oxime 大连理工大学 2021-06-22 CN claimed
US-8318085-B2 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. (US) 2012-11-27 US claimed
US-20120035086-A1 Methods and Compositions for Inhibiting Metal Corrosion HALLIBURTON ENERGY SERVICES, INC. (US) 2012-02-09 US claimed
US-8062586-B2 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. (US) 2011-11-22 US claimed
US-20100087340-A1 Methods and Compositions for Inhibiting Metal Corrosion HALLIBURTON ENERGY SERVICES, INC. 2010-04-08 US claimed
EP-1689911-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION Halliburton Energy Services, Inc. (US) 2006-08-16 EP claimed
WO-2005054544-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-06-16 WO claimed
US-20050123437-A1 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. 2005-06-09 US claimed
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons SICPA HOLDING SA (CH) 2025-12-30 US disclosed
EP-4069806-B1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2025-04-16 EP disclosed
US-20250051299-A1 PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE DAIKIN INDUSTRIES, LTD. (JP) 2025-02-13 US disclosed
US-12162854-B2 Production method for fluoromethyl derivative DAIKIN INDUSTRIES, LTD. (JP) 2024-12-10 US disclosed
US-20240327736-A1 METHOD OF MARKING A PETROLEUM HYDROCARBON SICPA HOLDING SA (CH) 2024-10-03 US disclosed
US-5936129-A PREVENTING BY-PRODUCT PRODUCTION OF CHEMICAL CONDENSATION REACTION, REACTING A HINDERED ALIPHATIC ESTER AND A KETONE IN PRESENCE OF A STRONG BASE AND A SOLVENT, REACTING THE FORMED SOLUTION WITH THE KETONE HENKEL CORPORATION (US) 1999-08-10 US disclosed
WO-1998033385-A1 PROCESS AND COMPOSITIONS FOR ENHANCING RELIABILITY OF EXOGENOUS CHEMICAL SUBSTANCES APPLIED TO PLANTS MONSANTO COMPANY (US) 1998-08-06 WO disclosed
US-4289914-A FREE RADICAL POLYMERIZATION INITIATORS, CURING AGENTS FOR UNSATURATED POLYESTERS PENNWALT CORPORATION (US) 1981-09-15 US disclosed
US-4257985-A Compounds by addition of hydroperoxides to α-β-unsaturated ketones PENNWALT CORPORATION (US) 1981-03-24 US disclosed
US-3948991-A Cyclic aldol condensation process and catalyst regeneration procedure GULF RESEARCH & DEVELOPMENT COMPANY (US) 1976-04-06 US disclosed
US-3946079-A METAL PHOSPHATE CATALYST TOKUYAMA SODA KABUSHIKI KAISHA (JA) 1976-03-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12162854-B2 Production method for fluoromethyl derivative AFF1, AFF2, ROS1 NFE2L2 251/4885MEN1 330/4885KMT2A 478/4885
US-12510529-B2 Method for determining authenticity and adulteration of marked petroleum hydrocarbons CYP4A11, CYP11B1, CYP11A1 NFE2L2 1077/4885MEN1 3758/4885KMT2A 3483/4885
US-20250051299-A1 PRODUCTION METHOD FOR FLUOROMETHYL DERIVATIVE AFF1, AFF2, ROS1 NFE2L2 251/4885MEN1 330/4885KMT2A 478/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.