SCHEMBL566978

SCHEMBL566978

CC(=CC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFE2L2 Q16236 1/20 0.61
MEN1 O00255 3/20 0.61
KMT2A Q03164 3/20 0.61
MAPK1 P28482 2/20 0.54
ALDH1A1 P00352 2/20 0.54
TDP1 Q9NUW8 1/20 0.54
HDAC1 Q13547 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC3 O15379 1/20 0.53
NCOR2 Q9Y618 1/20 0.53
AKT1 P31749 1/20 0.52
MAPT P10636 4/20 0.51
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
GAA P10253 2/20 0.51
THRB P10828 1/20 0.51
DEGS1 O15121 1/20 0.51
RECQL P46063 2/20 0.48
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1133764 1.00 NFE2L2 (0.61) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL566977 1.00 NFE2L2 (0.61) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL23086309 0.90 CES2 (0.57) NFE2L2MEN1KMT2AALDH1A1TDP1
SCHEMBL23086307 0.90 CES2 (0.57) NFE2L2MEN1KMT2AALDH1A1TDP1
SCHEMBL17129921 0.88 NFE2L2 (0.53) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL15080850 0.88 NFE2L2 (0.53) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL17129920 0.86 NFE2L2 (0.52) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL12720046 0.86 MEN1 (0.47) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL566675 0.84 NFE2L2 (0.64) NFE2L2MEN1KMT2AMAPK1ALDH1A1
SCHEMBL566351 0.84 DEGS1 (0.53) NFE2L2MEN1KMT2AMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 276 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2026-05-12 US claimed
EP-4707342-A2 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES Johnson & Johnson Vision Care, Inc. (US) 2026-03-11 EP claimed
US-20260044018-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE (US) 2026-02-12 US claimed
US-20260003209-A1 TORIC CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE (US) 2026-01-01 US claimed
US-12486348-B2 Contact lens displaying improved vision attributes JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-12-02 US claimed
US-20250362432-A1 OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS JOHNSON & JOHNSON VISION CARE (US) 2025-11-27 US claimed
US-12481173-B2 Multifocal contact lens displaying improved vision attributes JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-11-25 US claimed
EP-4022368-B1 CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES JOHNSON & JOHNSON VISION CARE (US) 2025-11-12 EP claimed
EP-4540638-A1 OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS Johnson & Johnson Vision Care, Inc. (US) 2025-04-23 EP claimed
US-12196916-B2 Polymerizable absorbers of UV and high energy visible light JOHSNON & JOHNSON VISION CARE, INC. (US) 2025-01-14 US claimed
EP-1187865-B1 METHOD FOR PRODUCING OF MATRESSES, UPHOLSTERIES FOR FURNITURE OR CARPET BACKINGS BASF AG (DE) 2005-11-09 EP claimed
WO-2005054544-A1 METHODS AND COMPOSITIONS FOR INHIBITING METAL CORROSION HALLIBURTON ENERGY SERVICES, INC. (US) 2005-06-16 WO claimed
US-20050123437-A1 Methods and compositions for inhibiting metal corrosion HALLIBURTON ENERGY SERVICES, INC. 2005-06-09 US claimed
CN-1124315-C Ocular devices mfd. with free radical polymerizable latent ultra-violet absorbers JOHNSON & JOHNSON VISIO PRODUC (US) 2003-10-15 CN claimed
US-6566138-B1 Fluorescent dye for use as diagnostic tool in monitor biological agents THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2003-05-20 US claimed
EP-1187865-A1 METHOD FOR PRODUCING POLYURETHANE FOAMS BASF AKTIENGESELLSCHAFT (DE) 2002-03-20 EP claimed
US-6218463-B1 Ocular devices manufactured with free radical-polymerizable latent ultra-violet absorbers JOHNSON & JOHNSON VISION CARE, INC. 2001-04-17 US claimed
WO-2000066643-A1 METHOD FOR PRODUCING POLYURETHANE FOAMS BASF AKTIENGESELLSCHAFT (DE) 2000-11-09 WO claimed
CN-1233630-A Ocular devices mfd. with free radical polymerizable latent ultra-violet absorbers JOHNSON & JOHNSON VISIO PRODUC (US) 1999-11-03 CN claimed
EP-0952467-A1 Ocular devices manufactured with free radical-polymerizable latent ultra-violet absorbers JOHNSON & JOHNSON VISION PRODUCTS, INC. (US) 1999-10-27 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12196916-B2 Polymerizable absorbers of UV and high energy visible light F12, F9, RECQL NFE2L2 2700/4885MEN1 828/4885KMT2A 4197/4885
US-20260044018-A1 MULTIFOCAL CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES NECTIN4, CRYAB, PSEN1 NFE2L2 251/4885MEN1 461/4885KMT2A 1647/4885
US-20260003209-A1 TORIC CONTACT LENS DISPLAYING IMPROVED VISION ATTRIBUTES TRPA1, LATS2, TEC NFE2L2 509/4885MEN1 1810/4885KMT2A 2622/4885
US-12624214-B2 Polymerizable absorbers of UV and high energy visible light CRY1, SCNN1G, MALT1 NFE2L2 2941/4885MEN1 941/4885KMT2A 1560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.