Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.68 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.66 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.64 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.64 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.64 |
| ▸ | PRKCA | P17252 | 1/20 | 0.64 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.62 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.60 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.60 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.60 |
| ▸ | CES2 | O00748 | 1/20 | 0.60 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.60 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670209 | 1.00 | DGKA (0.68) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL5668036 | 0.91 | MAPT (0.66) | DGKAENPP2LPAR3PRKCEPRKCQ | |
| SCHEMBL5665286 | 0.89 | MAPT (0.62) | DGKAENPP2LPAR3TDP1PRKCE | |
| SCHEMBL27013994 | 0.88 | ENPP2 (0.82) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL18127295 | 0.88 | PRKCA (0.72) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL13855468 | 0.87 | DGKA (0.66) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL12438334 | 0.86 | DGKA (0.73) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL2396742 | 0.86 | DGKA (0.73) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL332986 | 0.86 | DGKA (0.73) | DGKAENPP2LPAR3RECQLBLM | |
| SCHEMBL10655057 | 0.86 | DGKA (0.73) | DGKAENPP2LPAR3RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461041-A4 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD (BB) | 2006-03-29 | — | — | EP | disclosed |
| EP-1461041-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | Pharmasset Ltd. (BB) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003051298-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD. (BB) | 2003-06-26 | — | — | WO | disclosed |