Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1334451 | 0.91 | ADORA1 (0.47) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1332676 | 0.88 | ADORA1 (0.45) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1333167 | 0.85 | ADORA1 (0.44) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1333278 | 0.83 | ADORA1 (0.43) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL5653536 | 0.83 | ADORA1 (0.63) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1333186 | 0.82 | CNOT7 (0.47) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1332550 | 0.81 | ADORA2B (0.43) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1334837 | 0.81 | ADORA2B (0.44) | ADORA1ADORA2BADORA2AKMT2AADORA3 | |
| SCHEMBL5653534 | 0.80 | ADORA1 (0.41) | ADORA1ADORA2BADORA2AKMT2ARXFP1 | |
| SCHEMBL1334834 | 0.77 | ADORA3 (0.44) | ADORA1ADORA2BADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7247639-B2 | A1 adenosine receptor antagonists | ENDACEA, INC. (US) | 2007-07-24 | — | — | US | claimed |