Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 11/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13906449 | 0.67 | MCHR1 (0.41) | TRPV3CHRNA7KDM1AMAOBGAA | |
| SCHEMBL1396407 | 0.67 | KIF11 (0.38) | TRPV3KDM1AMAOBKIF11NISCH | |
| SCHEMBL6123983 | 0.65 | PARP1 (0.42) | TRPV3KDM1AMAOBKIF11NISCH | |
| SCHEMBL6124019 | 0.65 | PGR (0.36) | TRPV3KDM1AMAOBKIF11NISCH | |
| SCHEMBL11826597 | 0.64 | NISCH (0.50) | KIF11NISCHKDM4ENPC1POLB | |
| SCHEMBL12603819 | 0.64 | MCHR1 (0.43) | TRPV3CHRNA7GAA | |
| SCHEMBL2609383 | 0.63 | TRPV3 (0.51) | TRPV3KIF11POLB | |
| SCHEMBL29893246 | 0.63 | CYP11B1 (0.50) | TRPV3CHRNA7KDM1AMAOBATM | |
| SCHEMBL2609329 | 0.61 | SCN9A (0.56) | TRPV3KIF11 | |
| SCHEMBL1396656 | 0.61 | KIF11 (0.58) | KIF11NPC1POLBRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060100230-A1 | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2006-05-11 | — | — | US | disclosed |
| CN-1678581-A | Indolin phenylsulfonamide derivatives | BAYER HEALTHCARE AG (DE) | 2005-10-05 | — | — | CN | disclosed |
| EP-1519919-A1 | INDOLIN PHENYLSULFONAMIDE DERIVATIVES | Bayer HealthCare AG (DE) | 2005-04-06 | — | — | EP | disclosed |
| WO-2004005253-A1 | INDOLIN PHENYLSULFONAMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2004-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100230-A1 | Indolin phenylsulfonamide derivatives | PPARD, PPARA, PPARG | TRPV3 647/4885CHRNA7 1376/4885FLT3 1624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.