SCHEMBL5674236

SCHEMBL5674236

Cc1ccc(C(C)C)c(N=O)c1N=O

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.37
HTT P42858 2/20 0.37
GPR55 Q9Y2T6 1/20 0.37
TRPA1 O75762 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14001041 0.81 KMT2A (0.38) LMNAHTTTRPA1ALDH1A1MAPT
SCHEMBL13304710 0.79 GPR55 (0.33) LMNAHTTGPR55
SCHEMBL15236190 0.79 HTT (0.33) LMNAHTTGPR55ALDH1A1HPGD
SCHEMBL16919083 0.75 GABRA1 (0.48) LMNASLC6A2HTR2BHPGDKMT2A
SCHEMBL19336621 0.68 GABRA1 (0.41) LMNASLC6A2HTR2BHPGDKMT2A
SCHEMBL30782204 0.68 GABRA1 (0.41) LMNAHTTGPR55TRPA1CHRM1
SCHEMBL6933174 0.66 KMT2A (0.48) HTTTRPA1ALDH1A1MAPTKMT2A
SCHEMBL9394310 0.65 POLB (0.42) LMNAHTTALDH1A1HPGDMAPT
SCHEMBL3282798 0.65 ALDH1A1 (0.42) LMNAHTTTRPA1ALDH1A1HPGD
SCHEMBL14228285 0.64 LPAR1 (0.44) LMNASLC6A2HTR2BHPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1068258-B1 REINFORCED COMPOSITE AND ADHESIVE LORD CORP (US) 2006-01-04 EP disclosed
EP-1068258-A1 REINFORCED COMPOSITE AND ADHESIVE Lord Corporation (US) 2001-01-17 EP disclosed
US-6132870-A BLEND OF ELASTOMER, REINFORCING FIBERS AND ADHESIVE; CURING LORD CORPORATION (US) 2000-10-17 US disclosed
WO-1999050342-A1 REINFORCED COMPOSITE AND ADHESIVE LORD CORPORATION (US) 1999-10-07 WO disclosed