SCHEMBL6933174

SCHEMBL6933174

Cc1cccc(C)c1N=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.48
ATM Q13315 3/20 0.48
MAPT P10636 1/20 0.48
HSP90AA1 P07900 2/20 0.44
MEN1 O00255 1/20 0.44
MAPK8 P45983 1/20 0.43
MAPK9 P45984 1/20 0.43
MAPK10 P53779 1/20 0.43
CYP2A6 P11509 2/20 0.43
CYP1A2 P05177 1/20 0.43
TSHR P16473 1/20 0.42
ACHE P22303 1/20 0.42
ALDH1A1 P00352 3/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
HTT P42858 1/20 0.40
GRIN2D O15399 2/20 0.39
GRIN3B O60391 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL28202551 0.88 KMT2A (0.46) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL6050004 0.85 KMT2A (0.43) KMT2AATMMAPTHSP90AA1MEN1
Phenol SCHEMBL27915790 0.84 KMT2A (0.48) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL28144521 0.83 KMT2A (0.42) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL12329402 0.83 ACHE (0.48) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL8168365 0.83 CD44 (0.50) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL14094866 0.83 KMT2A (0.42) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL14256812 0.83 KMT2A (0.42) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL4755413 0.83 ATM (0.50) KMT2AATMMAPTHSP90AA1MEN1
SCHEMBL9965047 0.83 ALDH1A1 (0.48) KMT2AATMMAPTHSP90AA1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030109051-A1 Spin trap for use in biological systems RANDOX LABORATORIES LTD (IE) 2003-06-12 US claimed
EP-1302771-A2 Spin trap for use in biological systems Randox Laboratories Ltd. (GB) 2003-04-16 EP claimed
CN-1362405-A Nitroso compound and use of it as spin catching agent RANDOV LAB LTD (GB) 2002-08-07 CN claimed
US-4129740-A Process for the preparation of para-nitroso-diphenylhydroxylamines AKZONA INCORPORATED (US) 1978-12-12 US claimed
EP-3544986-B1 BRIDGED TRIARYLAMINES FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2020-12-23 EP disclosed
CN-104981460-B Synthesis of N-heterocyclic carbenes and intermediates thereof 圣安德鲁斯大学董事会 2018-01-23 CN disclosed
CN-105793236-B Dimethylbenzoic acid compound 伊莱利利公司 2017-10-10 CN disclosed
US-9765020-B2 Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis CELLIX BIO PRIVATE LIMITED (IN) 2017-09-19 US disclosed
US-9765020-B2 Dichlorophenyl-imino compounds and compositions, and methods for the treatment of mucositis CELLIX BIO PRIVATE LIMITED (IN) 2017-09-19 US disclosed
US-9738753-B2 Programmed degradation of polymers derived from biomass NDSU RESEARCH FOUNDATION (US) 2017-08-22 US disclosed
US-20160362380-A1 METHOD FOR DECARBOXYLATION OF AMINO ACIDS VIA IMINE FORMATION UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. 2016-12-15 US disclosed
US-20150307446-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS CELLIX BIO PRIVATE LIMITED (IN) 2015-10-29 US disclosed
US-20030109051-A1 Spin trap for use in biological systems RANDOX LABORATORIES LTD (IE) 2003-06-12 US disclosed
EP-1302771-A2 Spin trap for use in biological systems Randox Laboratories Ltd. (GB) 2003-04-16 EP disclosed
EP-1302771-A2 Spin trap for use in biological systems Randox Laboratories Ltd. (GB) 2003-04-16 EP disclosed
CN-1362405-A Nitroso compound and use of it as spin catching agent RANDOV LAB LTD (GB) 2002-08-07 CN disclosed
EP-0009267-B1 PROCESS FOR THE PREPARATION OF P-NITROSO-DIPHENYLHYDROXYLAMINES AKZO N.V. (NL) 1981-11-25 EP disclosed
US-4242523-A Process for the preparation of para-nitroso-diphenyl-hydroxylamines AKZONA INCORPORATED (US) 1980-12-30 US disclosed
EP-0009267-A1 Process for the preparation of p-nitroso-diphenylhydroxylamines AKZO N.V. (NL) 1980-04-02 EP disclosed
US-4129740-A Process for the preparation of para-nitroso-diphenylhydroxylamines AKZONA INCORPORATED (US) 1978-12-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160362380-A1 METHOD FOR DECARBOXYLATION OF AMINO ACIDS VIA IMINE FORMATION BCAT2, AADAT, BCAT1 KMT2A 1596/4885ATM 80/4885MAPT 942/4885
US-20150307446-A1 COMPOSITIONS AND METHODS FOR THE TREATMENT OF MUCOSITIS MUC1, SI, ALPI KMT2A 4850/4885ATM 2970/4885MAPT 2326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.